Results 31 to 40 of about 2,546 (158)

In Vitro Characterization of Neutralizing Hen Antibodies to Coxsackievirus A16. [PDF]

Int J Mol Sci, 2021
Coxsackievirus A16 (CA16) is one of the major causative agents of hand, foot, and mouth disease (HFMD). Children aged <5 years are the most affected by CA16 HFMD globally. Although clinical symptoms of CA16 infections are usually mild, severe complications, such as aseptic meningitis or even death, have been recorded.
Mwale PF, Lee CH, Huang PN, Tseng SN, Shih SR, Huang HY, Leu SJ, Huang YJ, Chiang LC, Mao YC, Wang WC, Yang YY.   +11 more
europepmc   +4 more sources

Circulating trends of hand, foot, and mouth disease in Hubei Province, China: Impact from the COVID-19 pandemic

Heliyon, 2023
Objectives: This study was performed to investigate the effect of non-pharmaceutical interventions on hand, foot, and mouth disease in Hubei Province China during the coronavirus disease 2019 pandemic.
Kangping Zhou, Zhihong Ding, Bin Hu, Jianbo Zhan, Kun Cai   +4 more
doaj   +1 more source

SHFL Post-Transcriptionally Restricts Coxsackievirus A16 In Vitro and In Vivo. [PDF]

Viruses
Coxsackievirus A16 (CVA16), a major etiological agent of hand, foot, and mouth disease, is increasingly contributing to neurological complications, with no vaccines or virus-specific antivirals currently available. To identify CVA16-restricting host factors, we investigated the role of the interferon-stimulated gene shiftless (SHFL), previously ...
Li H, Wang R, Li J, Duan W, Liang Y, Sun Q, Zhou J, Zhang Y.   +7 more
europepmc   +3 more sources

Coxsackievirus A16 [PDF]

Human Vaccines & Immunotherapeutics, 2013
Coxsackievirus 16 (CA16) is one of the major pathogens associated with hand, foot, and mouth disease (HFMD) in infants and young children. In recent years, CA16 and human enterovirus 71 (EV71) have often circulated alternatively or together in the Western Pacific region, which has become an important public health problem in this region. HFMD caused by
Qunying, Mao, Yiping, Wang, Xin, Yao, Lianlian, Bian, Xing, Wu, Miao, Xu, Zhenglun, Liang   +6 more
openaire   +2 more sources

Molecular Phylogeny of Coxsackievirus A16 [PDF]

Journal of Clinical Microbiology, 2014
We have read the article by [Zong et al.][1] with considerable interest ([1][2]). They described the molecular phylogeny of Coxsackievirus A16 (CVA16) in Shenzhen, China, from 2005 to 2009. In their paper, they claimed that “Subtype B2 could be further divided into clusters B2a, B2b, and B2c ...
Ting, Sun, Yiming, Liu, Yanjun, Zhang, Linfu, Zhou   +3 more
openaire   +2 more sources

Molecular phylogeny of modern coxsackievirus A16 [PDF]

Archives of Virology, 2007
A phylogenetic analysis of VP1 and VP4 nucleotide sequences of 52 recent CVA16 strains demonstrated two distinct CVA16 genogroups, A and B, with the prototype strain being the only member of genogroup A. CVA16 G-10, the prototype strain, showed a nucleotide difference of 27.7-30.2% and 19.9-25.2% in VP1 and VP4, respectively, in relation to other CVA16
D, Perera, M A, Yusof, Y, Podin, M H, Ooi, N T T, Thao, K K, Wong, A, Zaki, K B, Chua, Y A, Malik, P V, Tu, N T K, Tien, P, Puthavathana, P C, McMinn, M J, Cardosa   +13 more
openaire   +3 more sources

The spatial–temporal distribution and etiological characteristics of hand-foot-and-mouth disease before and after EV‑A71 vaccination in Kunming, China, 2017–2020

Scientific Reports, 2022
After vaccination with enterovirus 71 (EV-A71), the prevalence of hand-foot-and-mouth disease (HFMD) remained high, and the spatial–temporal distribution of enteroviruses changed.
Meifen Wang, Tao Chen, Junchao Peng, Yunjiao Luo, Lijiang Du, Zhiying Lu, Jianzhu He, Chunli Liu, Quan Gan, Wei Ma, Zhikuan Cun, Qiongmei Zheng, Weiying Chen, Yonglin Chen, Mei Han, Guojun Liu, Jiwei Li   +16 more
doaj   +1 more source

Hand, foot, and mouth disease (HFMD) in India: A review on clinical manifestations, molecular epidemiology, pathogenesis, and prevention

Indian Dermatology Online Journal, 2023
HFMD is a childhood viral disease initiated by enteroviruses (EVs). Symptoms are initiated with mild-to-moderate fever of short duration followed by oral and skin lesions.
Sanjaykumar Tikute, Mallika Lavania
doaj   +1 more source

Construction and characterization of an infectious clone of coxsackievirus A16 [PDF]

Virology Journal, 2011
AbstractBackgroundCoxsackievirus A16 (CVA16) is a member of theEnterovirusgenus of thePicornaviridaefamily and it is a major etiological agent of hand, foot, and mouth disease (HFMD), which is a common illness affecting children. CVA16 possesses a single-stranded positive-sense RNA genome containing approximately 7410 bases.
Liu Fei, Liu Qingwei, Cai Yicun, Leng Qibin, Huang Zhong   +4 more
openaire   +3 more sources

HAND, FOOT AND MOUTH DISEASE: A REVIEW

Jurnal Kedokteran Diponegoro, 2023
Background: Hand, foot and mouth disease or HFMD is a common childhood infectious disease mainly caused by coxsackievirus A16 (CVA 16) and enterovirus 71 (EV71). This HFMD disease can spread throughout the world and also cause outbreaks.
Lisa Lailatannur
doaj   +1 more source