Results 21 to 30 of about 2,546 (158)

Epidemiology and genetic characteristics of coxsackievirus A16 associated with hand-foot-mouth disease in Hangzhou city, Zhejiang province from 2021 to 2024 [PDF]

Frontiers in Microbiology
Hand-foot-mouth disease (HFMD) is a common acute infectious disease in children caused by various enteroviruses (EV). CV-A16 is one of the main pathogens of HFMD, leading to multiple outbreaks of HFMD worldwide, especially in the Asia-Pacific region ...
Qihao Xu, Qihao Xu, Xiaofeng Qiu, Xiaofeng Qiu, Yue Yu, Yue Yu, Yanping Wen, Yanping Wen, Guozhong Zhang, Guozhong Zhang, Jun Li, Jun Li   +11 more
doaj   +2 more sources

Rhombencephalitis and Coxsackievirus A16

Emerging Infectious Diseases, 2009
To the Editor: Hand, foot, and mouth disease (HFMD) is a common illness in children and is mainly caused by coxsackievirus A16 (CA16) and enterovirus 71 (EV71). Although its clinical course is usually uneventful and most patients experience a full recovery, serious neurologic complications, including encephalitis, can occur secondarily to HFMD caused ...
Kazuna Goto, Masafumi Sanefuji, Koichi Kusuhara, Yorihiro Nishimura, Hiroyuki Shimizu, Ryutaro Kira, Hiroyuki Torisu, Toshiro Hara   +7 more
doaj   +2 more sources

Coxsackievirus A16 in Viet Nam [PDF]

International Journal of Infectious Diseases, 2020
N. Le Nguyen Truc, T.A. Nguyen, H. Nguyen Thi Thu, N.T.N. Le, V. Hoang Minh Tu, T. Tran Tan, H. Vu Thi Ty, N. Nguyen Thi Han, N. Lam Anh, K. Truong Huu, M.T. Ha, C. Nguyen vanVinh, H.R. van Doorn, G. Thwaites, T. Le van   +14 more
doaj   +3 more sources

Safety and immunogenicity of an experimental live combination vaccine against enterovirus 71 and coxsackievirus A16 in rhesus monkeys [PDF]

Human Vaccines & Immunotherapeutics, 2020
Enterovirus 71 (EV-A71) and Coxsackievirus A16 (CV-A16) are the two most common pathogens causing hand, foot, and mouth disease (HFMD). Previously, we obtained one candidate live attenuated strain each for EV-A71 and CV-A16; here, we evaluated the safety
Ting Yang, Tianhong Xie, Xia Song, Dong Shen, Hua Li, Lei Yue, Qinfang Jiang, Fanli Zhu, Huaqing Meng, Runxiang Long, Rong Yang, Feiyu Luo, Zhongping Xie   +12 more
doaj   +2 more sources

Molecular mechanism of antibody neutralization of coxsackievirus A16. [PDF]

Nat Commun, 2022
AbstractCoxsackievirus A16 (CVA16) causes hand, foot and mouth disease in infants and young children. However, no vaccine or anti-viral agent is currently available for CVA16. Here, the functions and working mechanisms of two CVA16-specific neutralizing monoclonal antibodies (MAbs), 9B5 and 8C4, are comprehensively investigated.
Zhang C, Liu C, Shi J, Wang Y, Xu C, Ye X, Liu Q, Li X, Qiao W, Yin Y, Cong Y, Huang Z.   +11 more
europepmc   +4 more sources

Nephrotic syndrome in hand, foot and mouth disease caused by coxsackievirus A16: a case report

International Journal of Infectious Diseases, 2014
Some viruses, including certain members of the enterovirus genus, have been reported to cause nephrotic syndrome. However, no case of coxsackievirus A16 (CVA16)-related nephrotic syndrome has been reported so far. We describe a case of CVA16-related hand,
Hong-Tao Zhou, Bing Wang, Xiao-Yan Che
doaj   +3 more sources

Circulating Coxsackievirus A16 Identified as Recombinant Type A Human Enterovirus, China

Emerging Infectious Diseases, 2011
To determine the relationship of coxsackievirus A16 (CA16) to prototype CA16-G10, we conducted a phylogenetic analysis of circulating CA16 strains in China.
Ke Zhao, Xue Han, Guanjun Wang, Wei Hu, Wenyan Zhang, Xiao-Fang Yu   +5 more
doaj   +3 more sources

Acute Fulminant Cerebral Edema Caused by Coxsackievirus A6 Infection: A Case Report

Clinical Case Reports
In recent years, Coxsackievirus A6 (CV‐A6) has gradually replaced Enterovirus 71 (EV‐71) and Coxsackievirus A16 (CV‐A16) as the main pathogen causing hand foot mouth disease (HFMD) in China.
Kang An, Juan Qian
doaj   +2 more sources

Development and evaluation of an inactivated coxsackievirus A16 vaccine in gerbils. [PDF]

Emerg Microbes Infect, 2022
Coxsackievirus A16 (CVA16) is one of the major pathogens responsible for human hand, foot, and mouth disease (HFMD), which has threatened the health of young children, particularly in Asia-Pacific nations. Vaccination is an effective strategy for protecting children from CVA16 infection.
Sun YS, Xia Y, Xu F, Lu HJ, Mao ZA, Gao M, Pan TY, Yao PP, Wang Z, Zhu HP.   +9 more
europepmc   +4 more sources

A hSCARB2-transgenic mouse model for Coxsackievirus A16 pathogenesis. [PDF]

Virol J, 2021
Abstract Background Coxsackievirus A16 (CA16) is one of the neurotropic pathogen that has been associated with severe neurological forms of hand, foot, and mouth disease (HFMD), but its pathogenesis is not yet clear.
Chen Y, Li H, Yang J, Zheng H, Guo L, Li W, Yang Z, Song J, Liu L, Liu L.   +9 more
europepmc   +6 more sources