Results 41 to 50 of about 2,546 (158)

Seroprevalence of Enterovirus A71 and Coxsackievirus A16 in Healthy People in Shandong Province, China.

PLoS ONE, 2016
BackgroundHand, foot, and mouth disease has become very common in mainland of China in recent years, and enterovirus A71 and coxsackievirus A16 are its major etiologic factors. Here we investigated the seroprevalence of enterovirus A71 and coxsackievirus
Jian-Xing Wang, Shuang-Li Zhu, Jing Wang, Yi Lin, Yao-Wen Pei, Da-Peng Sun, Yong Zhang, Xian-Jun Wang, Wen-Bo Xu, Shu-Jun Ding   +9 more
doaj   +1 more source

Recombinant Human Enterovirus 71 in Hand, Foot and Mouth Disease Patients

Emerging Infectious Diseases, 2004
Two human enterovirus 71 (HEV71) isolates were identified from hand, foot and mouth disease patients with genome sequences that had high similarity to HEV71 (>93%) at 5′UTR, P1, and P2 and coxsackievirus A16 (CV-A16, >85%) at P3 and 3′UTR.
Yoke-Fun Chan, Sazaly AbuBakar
doaj   +1 more source

Type I Interferon-Induced TMEM106A Blocks Attachment of EV-A71 Virus by Interacting With the Membrane Protein SCARB2

Frontiers in Immunology, 2022
Enterovirus A71 (EV-A71) and Coxsackievirus A16 (CV-A16) are the main causative agents of hand, foot and mouth disease (HFMD) worldwide. Studies showed that EV-A71 and CV-A16 antagonize the interferon (IFN) signaling pathway; however, how IFN controls ...
Xuemin Guo, Xuemin Guo, Shinuan Zeng, Xiaoxin Ji, Xiaoxin Ji, Xiaobin Meng, Xiaobin Meng, Nanfeng Lei, Nanfeng Lei, Hai Yang, Hai Yang, Xin Mu, Xin Mu   +12 more
doaj   +1 more source

School outbreak of coxsackievirus A16 in Antipolo City, Philippines, October 2022. [PDF]

Western Pac Surveill Response J
Objective: An investigation team was deployed to determine the cause of an outbreak of a cluster of cases of fever and rash in a public elementary school in Antipolo City, Philippines, after the Public Health Unit was notified on 24 October 2022. The team also aimed to identify the source of the outbreak and to guide prevention measures.
Garcia DS, Alireza S Faiyaz MF,b, Rebato ND, Blanco-Payuyo MZ, Roca JB, Lat CG.   +5 more
europepmc   +4 more sources

Longitudinal study on enterovirus A71 and coxsackievirus A16 genotype/subgenotype replacements in hand, foot and mouth disease patients in Thailand, 2000–2017

International Journal of Infectious Diseases, 2019
Background: Enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) are the major causative agents of hand, foot and mouth disease (HFMD) worldwide, particularly in the Asia-Pacific region.
Pirom Noisumdaeng, Achareeya Korkusol, Jarunee Prasertsopon, Kantima Sangsiriwut, Kulkanya Chokephaibulkit, Anek Mungaomklang, Arunee Thitithanyanont, Rome Buathong, Ratigorn Guntapong, Pilaipan Puthavathana   +9 more
doaj   +1 more source

A Neonatal Mouse Model of Coxsackievirus A16 for Vaccine Evaluation [PDF]

Journal of Virology, 2012
ABSTRACTTo evaluate vaccine efficacy in protecting against coxsackievirus A16 (CA16), which causes human hand, foot, and mouth disease (HFMD), we established the first neonatal mouse model. In this article, we report data concerning CA16-induced pathological changes, and we demonstrate that anti-CA16 antibody can protect mice against lethal challenge ...
Qunying, Mao, Yiping, Wang, Rong, Gao, Jie, Shao, Xin, Yao, Shuhui, Lang, Chao, Wang, Panyong, Mao, Zhenglun, Liang, Junzhi, Wang   +9 more
openaire   +2 more sources

First isolation and genomic characterization of enterovirus A71 and coxsackievirus A16 from hand foot and mouth disease patients in the Lao PDR

New Microbes and New Infections, 2014
Enterovirus A71 (EV‐A71) and coxsackievirus A16 (CV‐A16) are major aetiological agents of hand, foot and mouth disease in Asia. We established the first genomic characterization of strains isolated in 2011 from Lao patients.
V.H. Nguyen, B. Sibounheuang, K. Phommasone, M. Vongsouvath, P.N. Newton, G. Piorkowski, C. Baronti, X. de Lamballerie, A. Dubot‐Pérès   +8 more
doaj   +1 more source

Dynamic changes of viral load and the duration of viral shedding in patients with hand, foot and mouth disease: a protocol for longitudinal study

BMC Infectious Diseases, 2022
Background The duration of virus shedding is necessary for determining the infectious period. But there were few quantitative studies on the changes of viral load and the law of the viral shedding in hand foot and mouth disease (HFMD) patients has not ...
Xiaoxia Duan, Chaoyong Zhang, Zhenhua Chen, Juan Liao, Yilan Zeng, Weiwei Huang, Xueling Ren, Xueqin Tang, Hongxia Peng, Delan Zhang, Xiao Wang, Ping Yuan, Lu Long   +12 more
doaj   +1 more source

Molecular epidemiology of human coxsackievirus A16 strains

Biomedical Reports, 2016
The hand, foot and mouth disease (HFMD) epidemics have mainly been caused by human enterovirus 71 and human coxsackievirus A16 (CA16), which circulated alternatively or together in the epidemic area. The aim of the present study was to provide guidance in the prevention and control of HFMD from CA16 infection.
Wenmin, Yu, Huanxin, Xu, Changchang, Yin
openaire   +3 more sources

Enterovirus A71 Infection, Thailand, 2017

Emerging Infectious Diseases, 2018
An outbreak of hand, foot and mouth disease among children in Thailand peaked in August 2017. Enterovirus A71 subgenogroup B5 caused most (33.8%, 163/482) cases. Severe disease (myocarditis and encephalitis) was observed in 1 patient.
Jiratchaya Puenpa, Chompoonut Auphimai, Sumeth Korkong, Sompong Vongpunsawad, Yong Poovorawan   +4 more
doaj   +1 more source