Results 71 to 80 of about 1,351 (168)

Permeability of Oral Tissues to Blood-borne Coxsackievirus B-1 [PDF]

Applied Microbiology, 1967
The ability of coxsackievirus B-1 to pass the barriers of the circulatory system into whole saliva has been shown previously. In this investigation, the major salivary glands and the oral mucosa were studied, and their role as participants in the excretion of coxsackievirus B-1 during viremia was evaluated.
J V, Madonia, A N, Bahn
openaire   +2 more sources

Extracellular Vesicles Released by Picornavirus‐Infected Cells Modify Antiviral Immune Cell Responses

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Naked viruses of the family Picornaviridae commonly spread via lysis of infected cells. Recent studies indicate that, prior to cell lysis, naked viruses are packaged and released inside extracellular vesicles (EVs). This has been considered a pro‐viral mechanism because EV membranes protect enclosed virions from neutralizing antibodies.
Xinyi Pei, Janine T. A. T. Stienstra, Margarida Viola, Renee G. C. Maas, Kyra A. Y. Defourny, Erik Mul, Saskia C. A. de Jager, Joost P. G. Sluijter, Frank J. M. van Kuppeveld, Esther N. M. Nolte‐‘t Hoen   +9 more
wiley   +1 more source

Cathepsin B aggravates coxsackievirus B3-induced myocarditis through activating the inflammasome and promoting pyroptosis. [PDF]

PLoS Pathogens, 2018
Cathepsin B (CatB) is a cysteine proteolytic enzyme widely expressed in various cells and mainly located in the lysosomes. It contributes to the pathogenesis and development of many diseases. However, the role of CatB in viral myocarditis (VMC) has never
Yaping Wang, Liangliang Jia, Jian Shen, Yidong Wang, Zurong Fu, Sheng-An Su, Zhejun Cai, Jian-An Wang, Meixiang Xiang   +8 more
doaj   +1 more source

Coxsackievirus and Type 1 Diabetes Mellitus: The Wolf's Footprints

, 2018
Enteroviruses are important environmental contributors to islet inflammation (insulitis) in type 1 diabetes mellitus (T1DM). A recent study characterized the proteomic alterations induced by Coxsackievirus type B (CVB) infection of human islets.
Eizirik, Decio L., Anne Op de Beeck, Decio L. Eizirik, Op De Beeck, Anne   +3 more
core   +1 more source

Molecular Characterization of Coxsackievirus B5 Isolates from Sewage, Italy 2016-2017 [PDF]

, 2019
Hereby, the partial Viral Protein 1 sequences of Coxsackievirus B5 (CV-B5) from sewage samples, collected in Italy from 2016 to 2017, were compared with those available in GenBank from clinical samples.
Cossu, Andrea, Fiore S., Giammanco G. M., Germinario C, Spertini S, Spertini S., Germinario C., Larocca AMV, Cossu A., Cicala, Antonella, Siragusa A, Buttinelli, Gabriele, Castiglia P., Larocca A. M. V., Zoni, Roberta, Buttinelli G., Fontana S., Gamper S., Veronesi, Licia, Giammanco GM, Gamper S, De Grazia S., Triassi M, Fontana S, Veronesi L, Triassi, Maria, Larocca, Angela Maria Vittoria, Fontana, Stefano, Siragusa, Angelo, Spertini, Silvia, Buttinelli G, De Grazia S, Triassi M., Stefanelli P., Pennino, Francesca, Gamper, Sabine, Cicala A., Pennino F, Germinario, Cinzia, Amato C., Castiglia, Paolo, Stefanelli P, Amato, Concetta, De Grazia, Simona, Castiglia P, Cossu A, Fiore S, Zoni R, Stefanelli, Paola, Cicala A, Amato C, Fiore, Stefano, Zoni R., Siragusa A., Veronesi L., Pennino F., SIRAGUSA, DANILO, Giammanco, Giovanni Maurizio   +57 more
core   +1 more source

Polyethylene Terephthalate Micro and Nanoplastics Induce Oxidative and Endoplasmic Reticulum Stress, Compromising Intestinal Epithelial Integrity and Viability

Allergy, EarlyView.
Sena Ardicli, Huseyn Babayev, Lihong Chang, Ozge Ardicli, Can Zeyneloglu, Yagiz Pat, Duygu Yazici, Xiaoqing Liu, Ezgi Irem Bektas, Carina Beha, Halil I. Akyildiz, Nazrin B. Mammadova, Muhammed Emin Sari, Beate Rückert, Raja Dhir, Ismail Ogulur, Kari C. Nadeau, Mubeccel Akdis, Cezmi A. Akdis   +18 more
wiley   +1 more source

Organoids: From Bench to Bedside Applications

MedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li, Rui Cao, Maochen Li, Zichao Tian, Huahao Fan, Bixia Hong, Xiaojuan Liu   +6 more
wiley   +1 more source

Long-term multimodal imaging in acute posterior multifocal placoid pigment epitheliopathy and association with coxsackievirus exposure.

PLoS ONE, 2020
The purpose of this study was to evaluate potential insights into the pathogenesis of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) using multimodal diagnostic imaging and laboratory evaluation in long-term follow-up. A retrospective,
Alexa L Li, Neal V Palejwala, Jessica G Shantha, Ghazala O'Keefe, Cecilia S Lee, Thomas Albini, Steven Yeh   +6 more
doaj   +1 more source

Solution structure of the coxsackievirus and adenovirus receptor domain 1

, 2004
The coxsackievirus and adenovirus receptor (CAR) mediates entry of coxsackievirus B (CVB) and adenovirus (Ad). The normal cellular function of CAR, which is expressed in a wide variety of tissue types, is thought to involve homophilic cell adhesion in ...
Jacobs, Amy, Caffrey, Michael, Laue, Thomas M., Jiang, Shaokai   +3 more
core   +1 more source

Regulation of Immune Checkpoints: From Molecular Mechanisms to Clinical Therapies

MedComm, Volume 7, Issue 6, June 2026.
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by unleashing antitumor immunity. This review comprehensively examines the molecular mechanisms underlying key immune checkpoints—including PD‐1/PD‐L1, CTLA‐4, and TIM‐3—and their clinical applications.
Qintao Ge, Liu Yu, Jiahe Lu, Aihetaimujiang Anwaier, Xiyue Xiao, Yonghao Chen, Dingwei Ye, Hailiang Zhang, Wenhao Xu, Wenbin Dai   +9 more
wiley   +1 more source