Results 61 to 70 of about 3,270,007 (313)

Recent development of enterovirus A vaccine candidates for the prevention of hand, foot, and mouth disease

Expert Review of Vaccines, 2018
Introduction: Hand, foot, and mouth disease (HFMD) is a childhood illness commonly caused by enterovirus A. Enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) are the most commonly identified viruses associated with HFMD. Recently, outbreaks caused
Chih-Yeu Fang, Chia-Chyi Liu
doaj   +1 more source

A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]

, 2017
Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel, Delgui, Laura Ruth   +1 more
core   +2 more sources

Coxsackievirus B4 Infection of Human Fetal Thymus Cells [PDF]

Journal of Virology, 2004
ABSTRACTThe infection of human fetal thymus organ cultures (FTOC) with coxsackievirus B4 E2 (CVB4 E2) was investigated. Both positive- and negative-strand viral RNA were detected by real-time quantitative reverse transcription-PCR (RT-PCR) in CVB4 E2-infected FTOC, which supported high yields of virus production (∼10650% tissue culture infective doses ...
Brilot, Fabienne, Geenen, Vincent, Hober, Didier, Stoddart, Cheryl   +3 more
openaire   +3 more sources

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Calcium signals and calpain-dependent necrosis are essential for release of coxsackievirus B from polarized intestinal epithelial cells [PDF]

, 2011
Coxsackievirus B (CVB), a member of the enterovirus family, targets the polarized epithelial cells lining the intestinal tract early in infection. Although the polarized epithelium functions as a protective barrier, this barrier is likely exploited by ...
Bergelson, JM, Bozym, RA, Cheung, KH, Coyne, CB, Morosky, SA, Patel, K, White, C   +6 more
core   +1 more source

Heparan Sulfates and Coxsackievirus-Adenovirus Receptor: Each One Mediates Coxsackievirus B3 PD Infection [PDF]

Journal of Virology, 2003
ABSTRACT Amino acid exchanges in the virus capsid protein VP1 allow the coxsackievirus B3 variant PD (CVB3 PD) to replicate in decay accelerating factor (DAF)-negative and coxsackievirus-adenovirus receptor (CAR)-negative cells. This suggests that molecules other than DAF and CAR are involved in attachment of this CVB3 variant to
A E, Zautner, U, Körner, A, Henke, C, Badorff, M, Schmidtke   +4 more
openaire   +2 more sources

Innate Viral Sensor MDA5 and Coxsackievirus Interplay in Type 1 Diabetes Development

Microorganisms, 2020
Type 1 diabetes (T1D) is a polygenic autoimmune disease characterized by immune-mediated destruction of insulin-producing β-cells. The concordance rate for T1D in monozygotic twins is ≈30–50%, indicating that environmental factors also play a role in T1D
Samuel I. Blum, H. Tse
semanticscholar   +1 more source

Bee products as alternatives in the treatment of viral infections

Journal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 33-54, 15 January 2026.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba, Łukasz Marek, Jerzy Stojko, Anna Rzepecka‐Stojko   +3 more
wiley   +1 more source

Echovirus 11 lineage I and other enteroviruses in hospitalized children with acute respiratory infection in Southern Italy, 2022- 2023

International Journal of Infectious Diseases
Objectives: A new variant of echovirus 11 (E11) infection is a major health concern in neonates. Here, we describe the clinical and virological characteristics of enterovirus (EV) infections in children hospitalized with acute respiratory infection in ...
Daniela Loconsole, Francesca Centrone, Anna Sallustio, Daniele Casulli, Riccardo Zagaria, Davide Sacco, Vito Colella, Nelhudoff Albano, Desiree Caselli, Fabio Cardinale, Paola Giordano, Ignazio Lofù, Nicola Laforgia, Maria Chironna   +13 more
doaj   +1 more source

MOLECULAR-EPIDEMIOLOGICAL INVESTIGATION OF THE OUTBREAK OF ASEPTIC MENINGITIS IN NOVOSIBIRSK REGION

Бюллетень сибирской медицины, 2016
The aim of this study was to investigate the outbreak of aseptic meningitis in theNovosibirskregion in 2008–2009. We studied genetic diversity and molecular-epidemiological characteristics of human enteroviruses that caused aseptic meningitis.
A. V. Demina, V. A. Ternovoi, M. Yu. Kartashov, V. B. Loktev   +3 more
doaj   +1 more source