Results 41 to 50 of about 14,514 (174)
Objectives: A new variant of echovirus 11 (E11) infection is a major health concern in neonates. Here, we describe the clinical and virological characteristics of enterovirus (EV) infections in children hospitalized with acute respiratory infection in ...
Daniela Loconsole +13 more
doaj +1 more source
MOLECULAR-EPIDEMIOLOGICAL INVESTIGATION OF THE OUTBREAK OF ASEPTIC MENINGITIS IN NOVOSIBIRSK REGION
The aim of this study was to investigate the outbreak of aseptic meningitis in theNovosibirskregion in 2008–2009. We studied genetic diversity and molecular-epidemiological characteristics of human enteroviruses that caused aseptic meningitis.
A. V. Demina +3 more
doaj +1 more source
2′‐FL's Depiction of the Human Physiological Function Landscape
The figure summarizes the multifaceted physiological effects of 2′‐fucosyllactose (2′‐FL), a major human milk oligosaccharide. The schematic illustrates the central role of the gut‐centered regulatory axis, where 2′‐FL modulates gut microbiota composition, promotes the production of short‐chain fatty acids and microbial metabolites, enhances mucus ...
Yushan Xiao +3 more
wiley +1 more source
Enteroviruses (EVs) are small, non-enveloped RNA viruses that can cause diverse clinical outcomes, particularly severe in patients with primary immunodeficiency (PID) due to their impaired ability to clear infections.
Imene Ben Salem +16 more
doaj +1 more source
Evidence for coxsackievirus infection in primary Sjögren's syndrome [PDF]
AbstractObjectivePrimary Sjögren's syndrome (SS) is an autoimmune disease characterized by activation of minor salivary gland (MSG) epithelial cells and B and T lymphocytic infiltrates. These findings have long encouraged the hypothesis that a persistent viral infection of the MSG epithelial cells may drive the autoimmune response; however, the ...
Antigoni, Triantafyllopoulou +2 more
openaire +2 more sources
ABSTRACT Coxsackievirus A16 (CVA16) is a major causative agent of hand, foot, and mouth disease (HFMD), yet efficient virus‐like particle (VLP)–based vaccine development remains challenging due to enteroviral structural complexity and the cytotoxicity of the 3CD protease required for polyprotein processing.
Hyun‐Soo Kim +5 more
wiley +1 more source
Acute Myocarditis: From Pathophysiology to Risk‐Stratified Management—A Clinical Review
Stepwise approach to patients with suspected acute myocarditis, integrating the 2024 American College of Cardiology (ACC) four‐stage classification (Stages A–D) and the 2025 European Society of Cardiology (ESC) inflammatory myopericardial syndrome (IMPS) framework. Step 1 (Initial Assessment): clinical presentation, first‐line investigations (ECG, high‐
Michele Golino +9 more
wiley +1 more source
Coxsackievirus B3 Activates Macrophages Independently of CAR-Mediated Viral Entry
Enteroviruses are a genus of small RNA viruses that are responsible for approximately one billion global infections annually. These infections range in severity from the common cold and flu-like symptoms to more severe diseases, such as viral myocarditis,
Yasir Mohamud +5 more
doaj +1 more source
Molecular determinants for virulence in coxsackievirus B1 infection [PDF]
Studies demonstrated that a strain derived from an infectious clone of coxsackievirus B1 (CVB1N) (N. Iizuka, H. Yonekawa, and A. Nomoto, J. Virol. 65:4867-4873, 1991) was 3 to 4 log10 less virulent than the myotropic Tucson strain of CVB1 (CVB1T) following intraperitoneal inoculation of newborn mice. Replacement of nucleotides (nt) 69 to 804 from the 5'
J E, Rinehart, R M, Gómez, R P, Roos
openaire +2 more sources
PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao +14 more
wiley +1 more source

