Viruses associated with pneumonia in adults. [PDF]
, 2012 Viral pneumonia, which is typically associated with disease in childhood, is increasingly recognized as causing problems in adults. Certain viruses, such as influenza virus, can attack fully immunocompetent adults, but many viruses take advantage of more-
Cesario, Thomas C
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Human picornaviruses associated with neurological diseases and their neutralization by antibodies [PDF]
, 2017 Picornaviruses are the most commonly encountered infectious agents in mankind. They typically cause mild infections of the gastrointestinal or respiratory tract, but sometimes also invade the central nervous system.
Ang +22 more
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Induction of cytopathic effect and cytokines in coxsackievirus B3-infected murine astrocytes [PDF]
, 2013 BACKGROUND: Coxsackievirus commonly infects children and occasionally causes severe meningitis and/or encephalitis in the newborn. The underlying mechanism(s) behind the central nervous system pathology is poorly defined. METHODS: It is hypothesized that
Dangui Zhang +7 more
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A battle between host and pathogen : the innate immune response and enterovirus evasion strategies [PDF]
, 2014 Infections with Coxsackieviruses are common and in most cases the infection is asymptomatic and efficiently cleared. On rare occasions, however, an infection can lead to severe diseases including myocarditis, hepatitis and ...
Lind, Katharina
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An RNA replication-center assay for high content image-based quantifications of human rhinovirus and coxsackievirus infections [PDF]
, 2010 Background: Picornaviruses are common human and animal pathogens, including polio and rhinoviruses of the enterovirus family, and hepatits A or food-and-mouth disease viruses.
Andreas Jurgeit +6 more
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Coxsackievirus and Adenovirus Receptor Cytoplasmic and Transmembrane Domains Are Not Essential for Coxsackievirus and Adenovirus Infection [PDF]
Journal of Virology, 1999 ABSTRACTCoxsackievirus and adenovirus receptor (CAR) from which the cytoplasmic domain had been deleted and glycosylphosphatidylinositol (GPI)-anchored CAR lacking both transmembrane and cytoplasmic domains were both capable of facilitating adenovirus 5-mediated gene delivery and infection by coxsackievirus B3.
X, Wang, J M, Bergelson
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Interactions between enteroviruses and the host : implications for type 1 diabetes [PDF]
, 2014 Type 1 diabetes (T1D) is a disease that results after a selective destruction of the insulin-producing β-cells in the pancreas. The lack of β-cells renders T1D patients completely unable to synthesize and secrete insulin, which leads to a life-long ...
Larsson, Pär
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Treatment of Neonatal Infection Caused by Coxsackievirus B3 [PDF]
Journal of Perinatology, 1999 Four male infants with early neonatal infection caused by coxsackievirus B3 (presumed in one case) exhibited severe thrombocytopenia and liver dysfunction at presentation. The three infants who were administered human normal immunoglobulin within 3 days of disease onset survived, while the fourth infant, who received the preparation 6 days after ...
H, Kimura +5 more
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Advanced Science, EarlyView.RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li +5 more
wiley +1 more source