Results 11 to 20 of about 817,924 (155)

Coxsackievirus B Infections Are Associated With the Risk of Islet Autoimmunity in Children With Strong Genetic Susceptibility to Type 1 Diabetes-Results From the TRIGR Divia Study. [PDF]

Diabetes Metab Res Rev
ABSTRACT Aims Especially, the coxsackievirus B group of enteroviruses has been linked to the development of islet autoimmunity and type 1 diabetes in genetically susceptible individuals. Our aim was to study the possible associations of 10 different microbial infections with islet autoimmunity in a large international prospective study.
Oikarinen M, Sioofy-Khojine A, Puustinen L, Cuthbertson D, Lehtonen J, Jouppila NVV, Ludvigsson J, Hakola L, Niinistö S, Erlund I, Knip M, Krischer JP, Virtanen SM, Hyöty H, TRIGR Investigators.   +14 more
europepmc   +3 more sources

Coxsackievirus A21, Enterovirus 68, and Acute Respiratory Tract Infection, China [PDF]

Emerging Infectious Diseases, 2012
During August 2006–April 2010, in Beijing, China, 2 rare human enterovirus serotypes, coxsackievirus A21 and enterovirus 68, were detected most frequently in human enterovirus–positive adults with acute respiratory tract infections.
Zichun Xiang, Richard Gonzalez, Zhong Wang, Lili Ren, Yan Xiao, Jianguo Li, Yongjun Li, Guy Vernet, Gláucia Paranhos-Baccalà, Qi Jin, Jianwei Wang   +10 more
doaj   +2 more sources

Enterovirus infections in children. [PDF]

Pediatr Investig
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Chen X, Guo L, Lei X, Zhao L, Hei M, Shen J, Yin J, Li F, Deng J, Liu G, Zhang Y, Xie Z.   +11 more
europepmc   +2 more sources

Rare But Specific B‐Cell Receptor Reactivity Against Coxsackievirus A24 in Primary Central Nervous System Lymphomas [PDF]

EJHaem
ABSTRACT Introduction Primary central nervous system lymphoma (PCNSL) remains a distinct and aggressive malignancy whose underlying antigenic triggers are largely unknown. While autoantigens such as neurabin‐I and SAMD14 have been implicated, the potential role of infectious agents in driving clonal B‐cell receptor selection within the central nervous ...
Kos I, Cetin O, Fadle N, Regitz E, Preuss K, Lohse S, Smola S, Hartmann S, Fend F, Klingel K, Scherer F, Schorb E, Bewarder M, Staber P, Thurner L.   +14 more
europepmc   +2 more sources

Pentavalent Sialic Acid Conjugates Block Coxsackievirus A24 Variant and Human Adenovirus Type 37 – Viruses That Cause Highly Contagious Eye Infections [PDF]

, 2020
Coxsackievirus A24 variant (CVA24v) and human adenovirus 37 (HAdV-37) are leading causative agents of the severe and highly contagious ocular infections acute hemorrhagic conjunctivitis and epidemic keratoconjunctivitis, respectively.
thilo, stehle, Rebecca, Thompson, Naresh, Chandra, Nitesh, Mistry, Emil, Johansson, Georg, Zocher, Mikael, Elofsson, Daniel L., Hurdiss, Weixing, Qian, Lars, Frängsmyr, C. David, Andersson, Niklas, Arnberg, Rémi, Caraballo   +12 more
core   +2 more sources

Replicase Gene of Coxsackievirus B3

, 1984
A cDNA copy covering two-thirds of the coxsackievirus B3 genomewas cloned in the PstI site of the pBR322 vector. A nucleotidesequence containing the gene for the viral replicase and the3' noncoding region of the coxsackievirus B3 genome was determined ...
Stålhanske, P.O.K., Pettersson, U., Lindberg, A Michael,   +2 more
core   +9 more sources

The Four-Way Stop Sign: Viruses, 12-Lipoxygenase, Islets, and Natural Killer Cells in Type 1 Diabetes Progression

Frontiers in Endocrinology, 2017
Natural killer (NK) cells represent an important effector arm against viral infection, and mounting evidence suggests that viral infection plays a role in the development of type 1 diabetes (T1D) in at least a portion of patients.
Michele L. Semeraro, Lindsey M. Glenn, Margaret A. Morris   +2 more
doaj   +1 more source

Myocarditis, disseminated infection, and early viral persistence following experimental coxsackievirus B infection of cynomolgus monkeys. [PDF]

PLoS ONE, 2013
Coxsackievirus B (CVB) infection is a common cause of acute viral myocarditis. The clinical presentation of myocarditis caused by this enterovirus is highly variable, ranging from mildly symptoms to complete hemodynamic collapse.
Cheryl E Cammock, Nancy J Halnon, Jill Skoczylas, James Blanchard, Rudolf Bohm, Christopher J Miller, Chi Lai, Paul A Krogstad   +7 more
doaj   +1 more source

Neonatal sepsis due to Coxsackievirus B3 complicated by liver failure and pulmonary hemorrhage

Case Reports in Perinatal Medicine, 2022
Coxsackievirus B3 (CVB3) is a single-stranded RNA included in the “Human Enterovirus B” category associated with multiple, even severe, health issues in humans. Newborns are at risk of life-threatening conditions due to enteroviral infections.
Thach Rasmey, Gitto Lorenzo
doaj   +1 more source

Fulminant type 1 diabetes mellitus associated with Coxsackievirus type B1 infection during pregnancy: a case report

Journal of Medical Case Reports, 2019
Background Fulminant type 1 diabetes is characterized by an intrinsic insulin deficiency resulting from the severe destruction of pancreatic β cells and it rapidly leads to ketoacidosis.
Takahiro Hayakawa, Yoshio Nakano, Kana Hayakawa, Hiroaki Yoshimatu, Yoshikazu Hori, Kazuki Yamanishi, Hirofumi Yamanishi, Takayuki Ota, Tokuzo Fujimoto   +8 more
doaj   +1 more source