DNAm landscape up to 4 months post SARS-CoV-2 infection: insights from four population-based cohorts. [PDF]
Matías-García PR +28 more
europepmc +1 more source
Rehabilitation needs of long COVID patients in British Columbia
Abstract Introduction COVID‐19 can result in persistent symptoms and functional impairment that significantly impact daily functioning, highlighting the need for targeted rehabilitation. However, there is a lack of data on what proportion of long COVID patients need rehabilitation and which types are required.
Débora M. Petry Moecke +6 more
wiley +1 more source
Abstract Objective This systematic review and meta‐analysis aimed to synthesize the current evidence on the efficacy of various technological interventions for gait rehabilitation in adults with incomplete spinal cord injury (iSCI). Literature survey MEDLINE (accessed by PubMed), Embase, Cochrane Central Register of Controlled Trials (Cochrane CENTRAL),
Emerson de Carvalho +3 more
wiley +1 more source
A biomimetic membrane platform for predictive screening and rational engineering of endosomally escaped lipid nanoparticle-CpG oligodeoxynucleotides delivery systems. [PDF]
Cui W +6 more
europepmc +1 more source
Biomaterial‐integrated electroporation establishes a programmable therapeutic interface that coordinates electric‐field modulation, transient or irreversible membrane permeabilization, cargo stabilization, and immune remodeling. This Review highlights how nanocarriers, hydrogels, and bioelectronic interfaces expand electroporation from conventional ...
Binbin Ji +13 more
wiley +1 more source
Maternal BMI associations with cord blood DNA methylation and mid-childhood adiposity. [PDF]
Brolly G +5 more
europepmc +1 more source
Staging concept for aging management: Definition, mechanism, and coping strategies
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang +6 more
wiley +1 more source
Epigenome-wide Mendelian randomization with multi-omics validation identifies epigenetic drivers of idiopathic pulmonary fibrosis. [PDF]
Li Z +7 more
europepmc +1 more source
Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin +3 more
wiley +1 more source

