Results 201 to 210 of about 196,785 (313)

Demographic and Clinical Characteristics of Early‐Onset Colorectal Cancer in Sweden and Finland: A Multicentre Retrospective Cohort Study Over Three Decades

Journal of Surgical Oncology, EarlyView.
ABSTRACT Colorectal cancer is the third most common cancer worldwide, and the proportion of individuals diagnosed under the age of 50 years, referred to as early‐onset colorectal cancer (EOCRC), is increasing. The aim of this study was to evaluate how the demographic and clinical features of EOCR in northern Sweden and Finland have changed over time ...
Melina Charalambidi, Tanja Hukkinen, Tuomas Kaprio, Sofia Edin, Mats Hjortborg, Cecilia Williams, Jaana Hagström, Caj Haglund, Richard Palmqvist, Karin Strigård, Camilla Böckelman, Ioannis Gkekas   +11 more
wiley   +1 more source

Sex-based considerations in the choice for a TLR9 or TLR7/8 agonist to arm the sentinel lymph node in early-stage melanoma. [PDF]

Oncoimmunology
Notohardjo JCL, Toffoli EC, Muijlwijk T, van den Hout MFCM, Kandiah V, Labots M, van de Ven R, van den Eertwegh AJM, de Gruijl TD.   +8 more
europepmc   +1 more source

Ménière's Disease: A Tri‐Decade Scoping Review of Treatment Trends and Evidence Quality

The Laryngoscope, EarlyView.
This tri‐decade scoping review of Ménière's disease literature reveals a significant increase in high‐level evidence and a clinical pivot toward hearing‐preserving interventions, such as intratympanic steroids and cochlear implants. However, a significant quality paradox has emerged, where adherence to standardized AAO‐HNS reporting and diagnostic ...
Ofir Zavdy, Teeraya Piyajarawong, Seamus Boyle, Ross O'Shea, John Rutka   +4 more
wiley   +1 more source

Identifying High‐Risk Children Safe for Same‐Day Discharge After Tonsillectomy

The Laryngoscope, EarlyView.
ABSTRACT Objective Current guidelines recommend overnight admission for children with severe obstructive sleep apnea (OSA) and obesity undergoing tonsillectomy, although most have uneventful postoperative courses. We aimed to identify low‐risk subgroups within this high‐risk population who may be candidates for same‐day discharge. Methods Retrospective
Amy Ho, Yann‐Fuu Kou, Christopher Liu, Cynthia S. Wang, Felicity Lenes‐Voit, Stephen R. Chorney, Kenneth Lee, Seckin Ulualp, Ron B. Mitchell, Romaine F. Johnson   +9 more
wiley   +1 more source

Epigenetic landscapes in human pancreatic islets reveal distinct drivers for adaptation to age and type 2 diabetes. [PDF]

Nat Commun
Maurin L, Marselli L, Boissel M, Pascat V, Suleiman M, Henriques E, De Luca C, Ning L, Fourcot M, Tesi M, Toussaint B, Amanzougarene S, Derhourhi M, Oger F, Burdet F, Canouil M, Cnop M, Ibberson M, Bonnefond A, Marchetti P, Froguel P, Khamis A.   +21 more
europepmc   +1 more source

CpG receptors [PDF]

Genome Biology, 2001
openaire   +1 more source

Accelerated Biological Aging Increases the Risk of Head and Neck Cancer: Insights From Genetic Instruments of Epigenetic Clocks

Molecular Carcinogenesis, EarlyView.
ABSTRACT Epigenetic clocks are robust biomarkers of biological aging and have been associated with cancer susceptibility. However, the relationship between genetically predicted epigenetic age acceleration and head and neck cancer risk remains unclear. Using a large case‐control study of 2189 head and neck squamous cell carcinoma (HNSCC) cases and 2189
Jiaqi Wang, Jie Deng, Yifan Xu, Chia‐Wen Tsai, Wen‐Shin Chang, Yang Deng, Maosheng Huang, Da‐Tian Bau, Guojun Li, Jian Gu   +9 more
wiley   +1 more source

An extrinsic enzyme-activatable fluorescent probe for high-contrast tumor imaging. [PDF]

Chem Sci
Guo Y, Du Y, Heng L, Miao H, Chen C, Zhang Q, Wang J, Shan Y, Chen Z, Li L.   +9 more
europepmc   +1 more source

Gait Alterations Due to DCC Gene Variants in Individuals with Congenital Mirror Movements

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Congenital Mirror Movement Syndrome (CMMS) involves involuntary movements on one side of the body while voluntary movements are performed on the other side. They disrupt left–right coordination and can be caused by a pathogenic variant in the DCC gene.
Nok‐Yeung Law, Shanie Desrosiers, Sinthiya Sivanesan, Helga Tonkov, Frédéric Charron, Frédéric Bretzner, Myriam Srour, Dorothy Barthélemy   +7 more
wiley   +1 more source

DNA Methylation Variation in Blood Cells may Impact Platelet Function. [PDF]

TH Open
Teichman J, Chen MH, Thibord F, Chan MV, Nkambule BB, Lachapelle AR, Ma J, Joehanes R, Liu C, Aponte AM, Panicker SR, Kanthi Y, Levy D, Johnson AD.   +13 more
europepmc   +1 more source