CpG 1018 augments mRNA vaccine-induced anti-tumor immunity by potentiating CD8+ T cell responses. [PDF]
Mol Ther OncolLi Y +6 more
europepmc +1 more source
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
iNew Medicine, EarlyView.ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
Epigenetic Aging in Brain Tissue of the Self-Fertilizing Vertebrate, <i>Kryptolebias marmoratus</i>. [PDF]
Ecol EvolBélik J, Silvestre F.
europepmc +1 more source
Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue
iNew Medicine, EarlyView.ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao +3 more
wiley +1 more source
<i>NOS1</i> hypermethylation may participate in the colorectal cancer development and be associated with its prognosis. [PDF]
EpigeneticsZhang Z +13 more
europepmc +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li +3 more
wiley +1 more source
Investigation of Specific IgG‐Secreting Cells in Congenital Toxoplasmosis: The TOXODIAG Study
Journal of Clinical Laboratory Analysis, EarlyView.This study addressed the difficulty of establishing a postnatal biological diagnosis of congenital toxoplasmosis, particularly in the absence of toxoplasmosis monitoring during pregnancy, as is the case in many countries. Our work presents an ELISPOT (Enzyme‐Linked Immunospot) method adapted for the detection of B lymphocytes primed to produce IgG ...
F. Migot‐Nabias +28 more
wiley +1 more source
Vipr2 Gene Expression Is Upregulated in the Nucleus Accumbens of Spontaneous Hypertensive Rats During Early Life. [PDF]
Neuropsychopharmacol RepAraki R, Kita A, Ago Y, Yabe T.
europepmc +1 more source