Results 191 to 200 of about 318,338 (358)

FUSE: data-driven functional segmentation of DNA methylation data. [PDF]

Bioinformatics
Holmström S, Häkkinen A, Lavikka K, Marchi G, Hautaniemi S, Lahtinen A.   +5 more
europepmc   +1 more source

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

Causal Interplay Between Inflammatory Cytokines and Lipid Metabolites in Serous Ovarian Carcinoma: Insights From a Genetic Association Study

Journal of Clinical Laboratory Analysis, EarlyView.
This study utilizes a two‐sample Mendelian randomization framework to establish a causal link between circulating inflammatory proteins, blood metabolites, and the risk of serous ovarian carcinoma. Our findings identify Interleukin‐8 as a significant risk factor and demonstrate that 1‐Palmitoyl‐GPG (16:0) acts as a metabolic mediator within this ...
Chong‐ze Yang, Lan‐hui Qin, Cheng‐can Huang, Xiao‐li Huang, Ying‐xia Yang, Wei Lan, Miao Fan   +6 more
wiley   +1 more source

Epigenetic Signatures of Ageing in Asian Elephants Revealed by Reduced Representation Bisulphite Sequencing. [PDF]

Evol Appl
Arai K, Inoue-Murayama M.
europepmc   +1 more source

CpG island characterisation [PDF]

, 2005
Ongenaert, Maté, Van Criekinge, Wim
core   +1 more source

CpG islands identification in DNA sequences using modified P-spectrum based algorithm

, 2021
Pardeep Garg, Sunil Sharma
openalex   +1 more source

Workforce Representation and Service in Shortage Areas: Outcomes of a HBCU College of Dentistry, Class 2004–2023

Journal of Dental Education, EarlyView.
ABSTRACT Purpose This study examines Howard University College of Dentistry's (HUCD) contributions to dental education, focusing on its role in strengthening workforce representation, expanding access to care in dental health professional shortage areas (DHPSAs) and medically underserved areas (MUAs), and addressing persistent oral health disparities ...
Marzia Mustamand, Minxuan Lan, Esther Childers, Cheryl Fryer, Kingsley Kanjin, Emma Ta‐Zhou, Najah Abduh, Whittley Deleveaux, Raheem Pierre, Gail Cherry‐Peppers, Reginald Salter, Deborah Nixon‐Willis, Tanya Greenfield, Dexter Woods, Andrea Jackson, Xinbin Gu   +15 more
wiley   +1 more source

MeCP2 gene dosage-dependent neurodevelopmentally restricted defects arise by aberrant activation of cell fate-determining bivalent genes. [PDF]

Nat Commun
Luoni M, Kubacki M, Giannelli SG, Morosi F, Di Berardino C, Iannielli A, Sessa A, Colasante G, Di Patrizio Soldateschi E, Lanzuolo C, Broccoli V.   +10 more
europepmc   +1 more source

グアニン四重鎖構造形成CpGオリゴデオキシヌクレオチドの免疫活性化機能に対する複合体の構成とサイズの影響に関する研究 [論文内容及び審査の要旨] [PDF]

Bui Thao Nguyen LE
openalex  

Tissue specific DNA methylation of CpG islands in normal human adult somatic tissues distinguishes neural from non-neural tissues

, 2010
Srimoyee Ghosh, Allan J. Yates, Michael C. Frühwald, Jeffrey C. Miecznikowski, Christoph Plass, Dominic J. Smiraglia   +5 more
openalex   +2 more sources