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Identification of Differentially Methylated CpG Sites in Fibroblasts from Keloid Scars [PDF]

open access: goldBiomedicines, 2020
As a part of an abnormal healing process of dermal injuries and irritation, keloid scars arise on the skin as benign fibroproliferative tumors. Although the etiology of keloid scarring remains unsettled, considerable recent evidence suggested that keloidogenesis may be driven by epigenetic changes, particularly, DNA methylation.
Mansour A. Alghamdi   +11 more
openalex   +5 more sources

Allele-specific gene expression patterns in primary leukemic cells reveal regulation of gene expression by CpG site methylation [PDF]

open access: hybrid, 2008
Lili Milani   +10 more
openalex   +1 more source

Hyper-physiologic mechanical cues, as an osteoarthritis disease relevant environmental perturbation, cause a critical shift in set-points of methylation at transcriptionally active CpG sites in neo-cartilage organoids [PDF]

open access: green, 2023
Niek G.C. Bloks   +8 more
openalex   +1 more source

APOE genotype-specific methylation patterns are linked to Alzheimer disease pathology and estrogen response

open access: yesTranslational Psychiatry
The joint effects of APOE genotype and DNA methylation on Alzheimer disease (AD) risk is relatively unknown. We conducted genome-wide methylation analyses using 2,021 samples in blood (91 AD cases, 329 mild cognitive impairment, 1,391 controls) and 697 ...
Rebecca Panitch   +9 more
doaj   +1 more source

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