We selected breast cancer‐specific DNA methylation markers using The Cancer Genome Atlas (TCGA). We analyzed the methylation and expression patterns of candidate genes in breast cancer cell lines, ctDNA, and tissue samples. The relationship between ctDNA methylation markers and the clinicopathological features of breast cancer patients was investigated.
Young Ju Jeong +6 more
wiley +1 more source
Longitudinal Profiling of DNA Methylation Reveals Age-Varying CpG Sites and Novel Insights Into Aging Heterogeneity. [PDF]
Jia X +11 more
europepmc +1 more source
Dissecting the pathogenic effects of ambient air pollution exposure and its blood DNA methylation markers on cardiovascular disease risk. [PDF]
Li W +6 more
europepmc +1 more source
Genomic footprinting reveals cell-type-specific binding of ubiquitous transcription factors [PDF]
Becker, Peter B. +2 more
core
Sequence of Immunological Events During IgE‐Mediated Allergic Reactions to Food
ABSTRACT Food allergies (FA) represent a significant global health burden. Upon allergen re‐exposure, allergic patients exhibit a sequence of symptoms that vary in terms of affected organ systems, severity, time of onset and allergen reactivity thresholds.
N. A. Nagy +7 more
wiley +1 more source
Inter-individual differentially methylated region-targeted EWAS reveals epigenetic signatures of early childhood adversity. [PDF]
Mayanagi T +17 more
europepmc +1 more source
Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm +9 more
wiley +1 more source
CRISPR-Cas9-induced double-strand breaks disrupt maintenance of epigenetic information. [PDF]
Wang M, Zhang Y, Bi C, Li M.
europepmc +1 more source

