Results 291 to 300 of about 164,158 (344)

In-Situ Self-Assembling Oligomeric Collagen Scaffold Enhances Vaccine Retention and Vaccine-Induced Humoral Immunity. [PDF]

Vaccines (Basel)
Hernandez-Franco JF, Gude S, Morrison RA, Castillo Perez D, Voytik-Harbin SL, HogenEsch H.   +5 more
europepmc   +1 more source

A highly abundant circular RNA from the RMST locus plays a role in posterior fossa ependymoma pathogenesis

Brain Pathology, EarlyView.
circRMST (hsa_circ_0099634) is by far the most abundant isoform from the RMST locus. It is highly expressed in cancer cells throughout ependymoma patient samples and is located in the cytoplasm. circRMST knockdown causes cell cycle arrest and induces differentiation, and it is a marker for poor prognosis. The figure is made using BioRender.
Ulvi Ahmadov, Charlotte W. Udengaard, Stine M. Vissing, Silke D. Nielsen, Kim‐Gwendolyn Dietrich, Benedicte Parm Ulhøi, Lasse S. Kristensen   +6 more
wiley   +1 more source

Core Promoters of Pig SOD2 Gene and Its Expression Regulation by DNA Methylation. [PDF]

Vet Sci
Zhao M, Pang Z, Jia C, Zhao S, Xia W, Li J, Tao C.   +6 more
europepmc   +1 more source

DysRegNet: Patient‐specific and confounder‐aware dysregulated network inference towards precision therapeutics

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Gene regulation is frequently altered in diseases in unique and patient‐specific ways. Hence, personalised strategies have been proposed to infer patient‐specific gene‐regulatory networks. However, existing methods do not scale well because they often require recomputing the entire network per sample.
Johannes Kersting, Olga Lazareva, Zakaria Louadi, Jan Baumbach, David B. Blumenthal, Markus List   +5 more
wiley   +1 more source

Investigating epigenetic biomarkers of age, sex, and disease in captive South African cheetahs (Acinonyx jubatus jubatus). [PDF]

PLoS One
Ysrael MC, Kubiski S, Moore CE.
europepmc   +1 more source

Atopic Dermatitis (AD) Related Cord Blood DNA Methylation Patterns Are Linked to Maternal AD

Allergy, EarlyView.
Laura Matzner, Johanna Denkena, Marey Messingschlager, Anke Seegebarth, Rosa Engelhardt, Zhuoxin Peng, Parastoo Kheiroddin, Sebastian D. Mackowiak, Hermann Brenner, Dietrich Rothenbacher, Naveed Ishaque, Michael Kabesch, Roland Eils, Jon Genuneit, Saskia Trump, Irina Lehmann   +15 more
wiley   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

Considerations for study design and analysis for ethically and culturally safe DNA methylation research in Aotearoa New Zealand. [PDF]

SSM Popul Health
Rolleston A, Jones GT, Earle NJ, Gibbs S, Pilbrow A, Faatoese A, Poppe KK, Henare K, Cameron VA, Macartney-Coxson D, Legget ME, Doughty RN.   +11 more
europepmc   +1 more source

Integration of epigenetics into ecotoxicology: insights and fundamental research needs

Biological Reviews, EarlyView.
ABSTRACT Epigenetics refers to heritable changes in genome function that occur without direct alterations to the DNA sequence. A multitude of environmental contaminants can influence the epigenetic marks of a genome. Changes of epigenetic marks including DNA methylation, histone modifications, and non‐coding RNAs can induce alterations at the gene ...
Albano Pinto, Jana Asselman, Patrícia Pereira, Joana Luísa Pereira   +3 more
wiley   +1 more source

Differential DNA methylation and gene expression in stem cell-derived cardiomyocytes from patients with and without a history of clozapine-induced myocarditis. [PDF]

J Psychiatry Neurosci
Marques D, Spindola L, Narang A, Vaziri N, Stavrum A, Jayaram M, Thomas N, Pantelis C, Le Hellard S, Hemberger M, Dean W, Greenway S, Bousman C.   +12 more
europepmc   +1 more source