Results 321 to 330 of about 164,158 (344)

Are CpG sites mutation hot spots in the dystrophin gene?

Human Molecular Genetics, 1994
Duchenne muscular dystrophy (DMD) and the milder allelic Becker muscular dystrophy (BMD) are X-linked neuromuscular disorders resulting from mutations in the 2.4-megabase gene encoding the protein dystrophin (1,2). Two thirds of the diseasecausing mutations are large deletions which occur in the 5' and the central portions of the gene; most of them can
N, Akalin, E, Zietkiewicz, W, Makałowski, D, Labuda   +3 more
openaire   +2 more sources

Hypermethylated CpG Sites in the MTR Gene Promoter in Preterm Placenta

Epigenomics, 2017
Altered maternal one-carbon metabolism influences placental DNA methylation patterns and 'programs' the fetus for noncommunicable diseases in adult life.Levels of plasma folate, vitamin B12, homocysteine, mRNA and protein levels of MTHFR and MTR enzymes in placenta were compared among women delivering preterm (n = 83) and term (n = 75).
Vinita V, Khot, Dilip K, Yadav, Smeeta, Shrestha, Lovejeet, Kaur, Deepali P, Sundrani, Preeti M, Chavan-Gautam, Savita S, Mehendale, Giriraj R, Chandak, Sadhana R, Joshi   +8 more
openaire   +2 more sources

Dissociation Kinetics of Echinomycin from CpG Binding Sites in Different Sequence Environments

Biochemistry, 1996
We have examined the kinetics of dissociation of echinomycin from CpG sites in several DNA fragments containing synthetic DNA inserts by a variation of the footprinting technique. Complexes of the ligand with radiolabeled DNA fragments were dissociated by adding an excess of unlabeled calf thymus DNA.
Fletcher, Michael C., Fox, Keith R.
openaire   +3 more sources

Frequency of spontaneous p53 mutations (CpG site) in breast cancer in Japan

Breast Cancer Research and Treatment, 1993
Sixty-five tumors of invasive ductal carcinoma of the breast were examined for p53 alteration by the reverse transcription-polymerase chain reaction-single strand conformation polymorphism (RT-PCR-SSCP) method and sequencing analysis. In total, 16 samples (24.6%) showed p53 gene alteration.
M, Sasa, K, Kondo, K, Komaki, T, Uyama, T, Morimoto, Y, Monden   +5 more
openaire   +2 more sources

Brain and other central nervous system tumor statistics, 2021

Ca-A Cancer Journal for Clinicians, 2021
Kimberly D Miller, Quinn T Ostrom, Carol Kruchko Ba   +2 more
exaly  

Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies

Ca-A Cancer Journal for Clinicians, 2022
Paolo Tarantino, Roberto Carmagnani Pestana, Shanu Modi   +2 more
exaly  

Cancer risk among World Trade Center rescue and recovery workers: A review

Ca-A Cancer Journal for Clinicians, 2022
Paolo Boffetta, Charles B Hall, Andrew C Todd   +2 more
exaly  

Soft‐tissue sarcoma in adults: An update on the current state of histiotype‐specific management in an era of personalized medicine

Ca-A Cancer Journal for Clinicians, 2020
Adriana C Gamboa, Alessandro Gronchi, Kenneth Cardona, Facs   +2 more
exaly  

Self-adaptive dual-metal-site pairs in metal-organic frameworks for selective CO2 photoreduction to CH4

Nature Catalysis, 2021
Hongliang Huang, Chunrui Wu
exaly  

Global cancer statistics

Ca-A Cancer Journal for Clinicians, 2011
Frank Bray
exaly