Results 31 to 40 of about 3,387 (115)
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran +5 more
wiley +1 more source
Two‐Dimensional Frameworks From Metal Oxo Clusters at Liquid Interfaces
A two‐dimensional analog of the hexagonally close‐packed UiO‐66 metal–organic framework is assembled as a Langmuir monolayer at liquid interfaces using preformed metal oxo clusters and tailor‐made organic linkers. Coordination‐driven self‐assembly governs film formation, while linker amphiphilicity confines growth to two dimensions.
Ajmal Roshan Unniram Parambil +10 more
wiley +1 more source
Abstract Objectives To assess factors associated with rapidly progressive interstitial lung disease (ILD) (RP‐ILD) at time of ILD diagnosis in a multicentric retrospective cohort study of antisynthetase syndrome (ASyS). We used a complementary unsupervised approach, hierarchical clustering, to delineate distinct phenotypes among ASyS patients with ILD.
Maxime Billotte +16 more
wiley +1 more source
Mercury in the Needle: A Case of Malicious Injection and Toxicity
ABSTRACT Intentional or accidental injection of mercury into soft tissue is rare. Mercury toxicity typically arises from ingestion or inhalation with instances of subcutaneous injection documented in a limited number of case studies. Most reported cases involve either accidental exposure or deliberate acts, often presenting as painful granulomas, with ...
Naghmeh Kian +5 more
wiley +1 more source
Background: Patients with chronic obstructive pulmonary disease (COPD) often have cardiovascular comorbidities. Patients of COPD with cardiovascular complications tend to have more symptoms and a higher mortality than do patients with COPD alone.
R. V. Raghu +14 more
doaj +1 more source
Prediabetes Associates With Musculoskeletal Alterations Independent of Total Body Adiposity
ABSTRACT Background Excess adiposity is a major risk factor for insulin resistance, prediabetes, and Type 2 diabetes and increases the risk for sarcopenia and osteosarcopenia later in life. It has been proposed that altered metabolic function and musculoskeletal status in people with obesity are directly linked, presumably because they share common ...
Alan Fappi +10 more
wiley +1 more source
Functional characterization of NRT1/PTR FAMILY transporters: looking for a needle in a haystack
Summary NRT1/PTR FAMILY (NPF) transporters play crucial roles in plant physiology and development due to their involvement in nitrogen nutrition and their ability to transport multiple signaling molecules and metabolites. Whereas most eukaryotic and prokaryotic NPF orthologs are peptide transporters, most flowering plant NPF transport other substrates ...
Laura Morales de Los Ríos +6 more
wiley +1 more source
ABSTRACT People with anorexia nervosa (AN) engage in dietary restriction and other weight loss behaviors that result in dangerously low body weight, leading to an increased risk for mortality and medical complications. Weight gain is one of the most important indicators of treatment progress and recovery for AN.
Danielle A. N. Chapa +10 more
wiley +1 more source
Ferredoxin‐dependent flavin thioredoxin reductases (FFTRs) regenerate reduced thioredoxin, sustaining dithiol–disulfide exchange reactions that regulate protein activity in select organisms. In cyanobacterial FFTRs, we describe the formation of a thiolate–flavin charge transfer complex, asynchronous reduction of the two FAD cofactors within the ...
Martha Minjarez‐Saenz +8 more
wiley +1 more source
ALK‐rearranged non–small cell lung cancer (NSCLC) represents a paradigm of precision oncology, but acquired resistance to second‐generation ALK tyrosine kinase inhibitors (TKIs) such as alectinib remains inevitable. We report a young, nonsmoker male with ALK‐positive metastatic NSCLC who achieved a sustained complete response (CR) to brigatinib ...
Akhil Kapoor +8 more
wiley +1 more source

