Results 41 to 50 of about 3,387 (115)

Development of an Interaction Model of the Protein–Nanocluster Interface by Machine Learning–Assisted Clustering of Amino Acids

Aggregate, Volume 6, Issue 12, December 2025.
An interaction model for the interface between ligand‐protected gold nanoclusters and proteins is developed using unsupervised machine learning techniques and validated by molecular dynamics simulations and density functional theory calculations. ABSTRACT The interactions that occur in the interface of proteins and ligand‐stabilised metal nanoclusters ...
Brenda Ferrari, Zohreh Fallah, Maya Khatun, Hannu Häkkinen   +3 more
wiley   +1 more source

Brain Structural Changes and Amyloid Burden Linked to Midlife Obesity and Insulin Resistance: Implications for Alzheimer's Disease Risk

Alzheimer's &Dementia, Volume 21, Issue S1, December 2025.
Abstract Background Midlife obesity and insulin resistance are established risk factors for Alzheimer's disease, but their impact on brain structure and amyloid and tau burden remains unclear. This study explored the associations of obesity (BMI ≥ 30 kg/m²) and insulin resistance (HOMA‐IR) with cortical thickness, brain volume, and PET‐derived amyloid ...
Soheil Mohammadi, Mahsa Dolatshahi, Paul K. Commean, Farzaneh Rahmani, Caitlyn Nguyen, LaKisha Lloyd, Mahshid Naghashzadeh, Sara Hosseinzadeh Kasani, Bettina Mittendorfer, Claude Sirlin, Tammie L.S. Benzinger, Joseph E. Ippolito, John C. Morris, Cyrus A. Raji   +13 more
wiley   +1 more source

Ischemic Preconditioning as a Myocardial Protection Strategy in CABG: Evidence from a Prospective Clinical Study

Albanian Journal of Trauma and Emergency Surgery
Introduction: Ischemic preconditioning (IP) is a method that may help protect the human heart from injury during cardiac surgery. It is believed that IP prepares the heart for upcoming prolonged ischemia by activating local protective mechanisms ...
Raif Cavolli, Dogan Kahraman, Ruchan Akar, Tumer Corapcioglu   +3 more
doaj   +1 more source

Selective cyclooxygenase-2 inhibition protects against myocardial damage in experimental acute ischemia

Clinics, 2009
BACKGROUND: Acute myocardial infarction is associated with tissue inflammation. Early coronary reperfusion clearly improves the outcome but may help propagate the inflammatory response and enhance tissue damage.
Alberto Carnieto Jr., Paulo Magno Martins Dourado, Protásio Lemos da Luz, Antonio Carlos Palandri Chagas   +3 more
doaj   +1 more source

Deciphering Persistent D‐Dimer Elevation in Paraquat Poisoning: A Mortality Assessment Case Study

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT A 74‐year‐old woman accidentally ingested an unknown amount of paraquat without suicidal intent. Quickly presenting with dysphagia and tongue and oral mucosa burns, she sought medical care. Admitted to the intensive care unit, by the third day of hospitalization, due to the need to be evaluated for respiratory problems.
Behrooz Hashemi Domeneh, Ali Parouhan, Kimia Mohammadi, Masoumeh Amiri, Sasan Shafiei   +4 more
wiley   +1 more source

Reversible ST‐T Segment Changes Induced by Anamorelin: A Case Report

Respirology Case Reports, Volume 13, Issue 11, November 2025.
Anamorelin, which has been approved for cancer cachexia in Japan, has been known to cause adverse events including QT prolongation and can lead to fatal arrhythmia. We report the first case of a male patient with non‐small cell lung cancer who showed ST‐T segment change following anamorelin.
Hayato Akaishi, Tomonori Makiguchi, Yuji Ishida, Takuya Shimanaka, Hisashi Tanaka, Kageaki Taima, Sadatomo Tasaka   +6 more
wiley   +1 more source

An Unusual Initial Manifestation of Pulmonary Embolism: Aseptic Cavitary Infarction With Pulmonary Hypertension—Case Report and Literature Review

Respirology Case Reports, Volume 13, Issue 10, October 2025.
We report a rare case of CTEPH presenting with an aseptic cavitary pulmonary infarction, an unusual manifestation typically mimicking infection or malignancy. This case underscores the need for genetic screening in unexplained CTEPH, as thrombophilia workup in our case revealed a heterozygous Factor V Leiden mutation (an uncommon congenital risk factor
Vinay Venugopal, Saurabh Karmakar, Rajesh Kumar Yadav, Abdul Raouf Wani, Debapriya Maji, Gaurav Kumar Singh   +5 more
wiley   +1 more source

Multimarker risk stratification approach and cardiovascular outcomes in patients with stable coronary artery disease undergoing elective percutaneous coronary intervention

Indian Heart Journal, 2016
Aims: We studied the utility of multimarker risk stratification approach to predict cardiovascular outcomes in patients with stable coronary artery disease, undergoing elective percutaneous coronary intervention (PCI). Methods: We prospectively evaluated
Vimal Mehta, Rishi Sukhija, Pratishtha Mehra, Anuj Goyal, Jamal Yusuf, Bhawna Mahajan, V.K. Gupta, Sanjay Tyagi, Chandrasekar Palaniswamy, Wilbert S. Aronow   +9 more
doaj   +1 more source

Evaluation of an Ayurvedic polyherbal formulation (Sindhuvaradi agada) in Doxorubicin induced Cardiotoxicity- in wistar rats

Indian Journal of Ayurveda and Integrative Medicine KLEU, 2018
Background: Presently cancer is second major cause of death in India. Doxorubicin, an anthracycline is frequently used to treat various human malignancies but at same time its use is warranted with irreversible cardiomyopathy.
Shrutika Subhash Karoshi, Kolume Dugeppa Govindappa, Kalanghot Padmanabhan Skandhan   +2 more
doaj  

Correlating Thompson score and cardiac dysfunction in neonates suffering from perinatal asphyxia – A prospective observational study

Asian Journal of Medical Sciences
Background: Perinatal asphyxia continues to be a leading cause of neonatal morbidity and mortality worldwide. It causes multiorgan failure with brain involvement as the major organ of concern (hypoxic-ischemic encephalopathy). Cardiac dysfunction is also
Anushka Nag , Bhaswati Ghoshal , Meghna Siddhanta   +2 more
doaj   +1 more source