The two-component system CpxAR is required for the high potassium stress survival of Actinobacillus pleuropneumoniae [PDF]
Frontiers in Microbiology, 2023 IntroductionActinobacillus pleuropneumoniae is an important respiratory pathogen, which can cause porcine contagious pleuropneumonia and lead to great economic losses to worldwide swine industry.
Jiajia Wan +11 more
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CpxAR of Actinobacillus pleuropneumoniae Contributes to Heat Stress Response by Repressing Expression of Type IV Pilus Gene apfA [PDF]
Microbiology Spectrum, 2022 Acute pleuropneumonia in swine, caused by Actinobacillus pleuropneumoniae, is characterized by a high and sustained fever. Fever creates an adverse environment for many bacteria, leading to reduced bacterial proliferation; however, most pathogenic ...
Feng Liu +7 more
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Reassessing the role of the Escherichia coli CpxAR system in sensing surface contact. [PDF]
PLoS ONE, 2018 For proper biofilm formation, bacteria must have mechanisms in place to sense adhesion to surfaces. In Escherichia coli, the CpxAR and RcsCDB systems have been reported to sense surfaces.
Tom E P Kimkes, Matthias Heinemann
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The inner membrane protein YhiM links copper and CpxAR envelope stress responses in uropathogenic E. coli [PDF]
mBioUrinary tract infection (UTI) is a ubiquitous infectious condition, and uropathogenic Escherichia coli (UPEC) is the predominant causative agent of UTI. Copper (Cu) is implicated in innate immunity, including against UPEC.
Panatda Saenkham-Huntsinger +4 more
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The CpxAR Two-Component System Contributes to Growth, Stress Resistance, and Virulence of Actinobacillus pleuropneumoniae by Upregulating wecA Transcription [PDF]
Frontiers in Microbiology, 2020 Actinobacillus pleuropneumoniae is the pathogen of porcine contagious pleuropneumonia. In A. pleuropneumoniae, the CpxAR two-component system is essential for fitness and growth. The O-antigen protrudes from the outer membrane to the exterior of the cell,
Kang Yan +19 more
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The two-component system CpxAR controls biofilm formation by directly regulating the T3SS needle tip protein EseB in Edwardsiella piscicida [PDF]
Applied and Environmental MicrobiologyThe type III secretion system (T3SS) translocon protein EseB (needle tip protein) forms filamentous appendages on the surface of Edwardsiella piscicida to facilitate autoaggregation and biofilm formation. By contrast, another T3SS translocon protein EseC
Shu Ya Zhang +5 more
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Correction: The two-component system CpxAR is required for the high potassium stress survival of Actinobacillus pleuropneumoniae [PDF]
Frontiers in MicrobiologyJiajia Wan +11 more
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The two-component system CpxA/CpxR is critical for full virulence in Actinobacillus pleuropneumoniae [PDF]
Frontiers in Microbiology, 2022 Actinobacillus pleuropneumoniae, a major bacterial porcine respiratory tract pathogen causing pig pleuropneumonia, has resulted in high economic losses worldwide.
Feng Liu +10 more
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Journal of Microbiology, Immunology and Infection, 2023 Background: CpxAR is a two-component system that allows bacteria to reorganize envelope structures in response to extracellular stimuli. CpxAR negatively affects type 1 fimbriae expression in Klebsiella pneumoniae CG43, a hypervirulent strain.
Chih-Hao Kuo +5 more
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Characterization of the Role of Two-Component Systems in Antibiotic Resistance Formation in Salmonella enterica Serovar Enteritidis [PDF]
mSphere, 2022 The two-component system (TCS) is one of the primary pathways by which bacteria adapt to environmental stresses such as antibiotics. This study aimed to systematically explore the role of TCSs in the development of multidrug resistance (MDR) in ...
Mengjun Hu +7 more
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