The Varied Role of Efflux Pumps of the MFS Family in the Interplay of Bacteria with Animal and Plant Cells [PDF]
Efflux pumps represent an important and large group of transporter proteins found in all organisms. The importance of efflux pumps resides in their ability to extrude a wide range of antibiotics, resulting in the emergence of multidrug resistance in many
Barras, Frederic +7 more
core +3 more sources
Zinc stress induces copper depletion in Acinetobacter baumannii [PDF]
Background: The first row transition metal ions zinc and copper are essential to the survival of many organisms, although in excess these ions are associated with significant toxicity.
Eijkelkamp, B. +6 more
core +6 more sources
Surface sensing in Escherichia coli [PDF]
Adhesion of the bacterium Escherichia coli to a surface can lead to initiation of biofilm formation, which is a medically relevant process. However, little is known about how adhesion is perceived and which surface sensing systems are involved.
Kimkes, Tom Eric Pieter
core +6 more sources
How bacteria recognise and respond to surface contact [PDF]
Bacterial biofilms can cause medical problems and issues in technical systems. While a large body of knowledge exists on the phenotypes of planktonic and of sessile cells in mature biofilms, our understanding of what happens when bacteria change from the
Heinemann, Matthias, Kimkes, Tom E. P.
core +1 more source
Adaptive Laboratory Evolution of Antibiotic Resistance Using Different Selection Regimes Lead to Similar Phenotypes and Genotypes [PDF]
Antibiotic resistance is a global threat to human health, wherefore it is crucial to study the mechanisms of antibiotic resistance as well as its emergence and dissemination.
Ellabaan, Mostafa M Hashim +3 more
core +2 more sources
Development and validation of a high-throughput cell-based screen to identify activators of a bacterial two-component signal transduction system [PDF]
CpxRA is a two-component signal transduction system (2CSTS) found in many drug-resistant Gram-negative bacteria. In response to periplasmic stress, CpxA autophosphorylates and donates a phosphoryl group to its cognate response regulator, CpxR ...
Chen, Lan +8 more
core +1 more source
Gene clusters reflecting macrodomain structure respond to nucleoid perturbations
Focusing on the DNA-bridging nucleoid proteins Fis and H-NS, and integrating several independent experimental and bioinformatic data sources, we investigate the links between chromosomal spatial organization and global transcriptional regulation.
Alberts +89 more
core +2 more sources
The role of Ovotransferrin in egg-white antimicrobial activity: a review [PDF]
Eggs are a whole food which affordably support human nutritional requirements worldwide. Eggs strongly resist bacterial infection due to an arsenal of defensive systems, many of which reside in the egg white.
Andrews, Simon C. +9 more
core +2 more sources
Research progress on mechanism of surface sensing in Escherichia coli
Escherichia coli is a kind of facultative anaerobic bacteria which is commonly found in the host gastrointestinal tract and natural environments. The presence of pathogenic E.
WANG Liliang +4 more
doaj +1 more source
Bifidobacterial Dominance of the Gut in Early Life and Acquisition of Antimicrobial Resistance. [PDF]
Bifidobacterium species are important commensals capable of dominating the infant gut microbiome, in part by producing acids that suppress growth of other taxa.
Ahmad, SM +7 more
core +1 more source

