Iron Acquisition Mechanisms and Their Role in the Virulence of Burkholderia Species [PDF]
Burkholderia is a genus within the β-Proteobacteriaceae that contains at least 90 validly named species which can be found in a diverse range of environments. A number of pathogenic species occur within the genus.
Butt, A.T., Thomas, M.S.
core +4 more sources
Unraveling the role of UilS, a urea-induced acyl-homoserine lactonase that enhances Serratia marcescens fitness, interbacterial competition, and urinary tract infection. [PDF]
UNLABELLED: IMPORTANCE: This work reveals the acyl-homoserine ...
Tuttobene MR +7 more
europepmc +3 more sources
The CpxAR two‐component system is present in many Proteobacteria. It controls expression of genes required to maintain envelope integrity in response to environmental injury. Consequently, this two‐component system was shown to be required for virulence of several zoo‐pathogens, but it has never been investigated in phyto‐pathogens.
Bontemps-Gallo, Sébastien +2 more
openaire +3 more sources
Extracytoplasmic stress response systems in S. Typhimurium [PDF]
Salmonella species can cause wide-ranging disease from mild food-poisoning enteritis to a systemic, sometimes fatal typhoid infection. These bacteria have evolved to survive in different environments within and outside the host and do so through the ...
Lewis, Claire
core +3 more sources
The human gastrointestinal tract provides a complex environment for bacterial pathogens, necessitating their adaptation to host defenses and microbiota.
Rita Trirocco, Gianni Prosseda
doaj +1 more source
Multiomics analysis provides insight into the laboratory evolution of Escherichia coli towards the metabolic usage of fluorinated indoles [PDF]
Organofluorine compounds are known to be toxic to a broad variety of living beings in different habitats and chemical fluorination has been historically exploited by mankind for the development of therapeutic drugs or agricultural pesticides.
Agostini, Federica +9 more
core +2 more sources
The outer membrane (OM) of Gram-negative bacteria is the outermost layer of the cell and serves as permeability barrier against environmental toxins, including antibiotics.
Julianna Marotta +3 more
doaj +1 more source
Multiple, weak hits confuse complex systems: A transcriptional regulatory network as an example [PDF]
Robust systems, like the molecular networks of living cells are often resistant to single hits such as those caused by high-specificity drugs. Here we show that partial weakening of the Escherichia coli and Saccharomyces cerevisiae transcriptional ...
P. Erdős +5 more
core +1 more source
An Overview of Two-Component Signal Transduction Systems Implicated in Extra-Intestinal Pathogenic E. coli Infections [PDF]
Extra-intestinal pathogenic E. coli (ExPEC) infections are common in mammals and birds. The predominant ExPEC types are avian pathogenic E. coli (APEC), neonatal meningitis causing E. coli/meningitis associated E.
Allison R. Eberly +3 more
core +1 more source
The EnvZ-OmpR Two-Component Signaling System Is Inactivated in a Mutant Devoid of Osmoregulated Periplasmic Glucans in Dickeya dadantii [PDF]
Osmoregulated periplasmic glucans (OPGs) are general constituents of alpha-, beta-, and gamma-Proteobacteria. This polymer of glucose is required for full virulence of many pathogens including Dickeya dadantii (D. dadantii).
Brigitte Delrue +5 more
core +1 more source

