Results 61 to 70 of about 21,640 (247)
Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi+11 more
wiley +1 more source
OBJECTIVE: to identify factors which constrain or determine the return to sexual activity in the puerperium. METHOD: exploratory and descriptive study undertaken in a university hospital in the South of Brazil.
Cleci de Fátima Enderle+5 more
doaj
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez+8 more
wiley +1 more source
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang+6 more
wiley +1 more source
AISI 304L stainless steel powder is mixed with silicon nitride (Si3N4) powder and processed by PBF‐LB/M, allowing partial retention of Si3N4. The numerical approach effectively predicts the Si3N4 powder homogeneity and N content distribution on the powder bed. Recent studies have focused on the alloying of nitrogen (N) in high‐alloy stainless steels by
Yuanbin Deng+7 more
wiley +1 more source
The African hedgehog is one of the newly imported exotic pets which have been observed with increasing regularity in veterinary clinics in Costa Rica. Despite their popularity, information about their diseases is scarce. Within skin diseases of hedgehogs,
Andrés Moreira+2 more
doaj
Low-energy structure of 61Mn populated following $\beta$ decay of 61Cr
$\beta$ decay of the $^{61}$Cr$_{37}$ ground state has been studied. A new half-life of 233 +/- 11 ms has been deduced, and seven delayed $\gamma$ rays have been assigned to the daughter, $^{61}$Mn$_{36}$. The low-energy level structure of $^{61}$Mn$_{36}
Berryman, J. S.+14 more
core +1 more source
In this study, exciting new bi‐/multi‐linear elastic behavior of soft elastic composites that accompany the activation of wrinkling in the embedded interfacial layers is analyzed. The new features and performance of these composite materials, including dramatic enhancements in energy storage, can be tailored by the concentration of interfacial layers ...
Narges Kaynia+2 more
wiley +1 more source
Analysis of webs of partial-tension-field beams subjected to lateral pressure loadings [PDF]
Webs of partial-tension-field beams subjected to lateral pressure ...
Furuike, T.+3 more
core +1 more source