Results 61 to 70 of about 720,628 (278)

Identification of anthropogenic source of Pb and Cd within two tropical seagrass species in South China: Insight from Pb and Cd isotopes

open access: yesEcotoxicology and Environmental Safety
Seagrass beds are susceptible to deterioration and heavy metals represent a crucial impact factor. The accumulation of heavy metal in two tropical seagrass species were studied in South China in this study and multiple methods were used to identify the ...
Ling Zhang   +7 more
doaj   +1 more source

Exposure risks of trace metal(loid)s on little egrets in a restored polymetallic mining area in eastern China

open access: yesGlobal Ecology and Conservation, 2023
Trace metal(loid) pollution from mining activities is a widespread environmental problem, which has stimulated restoration efforts over the world. Tongling is a non-ferrous metal mining area in China with a long history of mining activities.
Chengze Liu   +4 more
doaj   +1 more source

YTHDC1 Orchestrates Glucose and Glutamate Rewiring to Overcome Lethal Metabolic Stress in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Lai et al. find that m6A reader YTHDC1 is specifically overexpressed in triple‐negative breast cancer (TNBC) and orchestrates glucose and glutamine metabolism in an m6A‐dependent manner to confer robust adaptability to lethal metabolic stress. Leveraging YTHDC1 knockdown‐induced metabolic vulnerability, an ATF4 mRNA‐targeted nanotherapy is developed to
Zheng‐Hao Lai   +12 more
wiley   +1 more source

Metal–Metal Cooperative C─F and S─F Bond Cleavage by Low‐Valent Tetracobalt Clusters and Water‐Assisted Fluoroarene Hydrodefluorination

open access: yesAngewandte Chemie, EarlyView.
Self‐assembled tetrahedral CoI4 clusters supported by simple bipyridine‐based ligands undergo core rearrangement to cleave S─F and C(sp2)─F bond, forming fluoride‐bridged tetracobalt(II)‐oxo clusters, while exposure of cobalt(I) clusters to molecular oxygen yields cubane‐type cobalt(III) oxo clusters.
Hoan M. Dinh   +4 more
wiley   +2 more sources

Evaluation of Radioactivity and Heavy Metal Concentrations in Some Liquid Supplements Samples

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences
In recent years, it has become clear that consumers of nutritional supplements, especially adults, tend to consume these supplements for the purpose of improving health and delaying chronic diseases associated with age, in addition to improving physical
Sarah Amir Abdalabass   +1 more
doaj   +1 more source

Antigen‐Detected NMR for Minimal Epitope Engineering and Structure‐Guided Selection of a NaV1.7‐Selective Nanobody

open access: yesAdvanced Science, EarlyView.
A minimal extracellular epitope from voltage‐gated sodium channel NaV1.7 was engineered into an isotope‐labelled antigen for antigen‐detected nuclear magnetic resonance (NMR). Together with AlphaFold2 (AF2), this enabled structure‐guided selection of R4C8, a human NaV1.7‐selective nanobody that labels fixed NaV1.7‐expressing cells and produces staining
Junyu Liu   +27 more
wiley   +1 more source

Spectra of He Isotopes and the 3He/4He Ratio

open access: yesThe Astrophysical Journal
Since its launch, the Alpha Magnetic Spectrometer-02 (AMS-02) has delivered outstanding quality measurements of the spectra of cosmic-ray (CR) species, e ^± , $\bar{p}$ , and nuclei (H–Si, S, Fe), which have resulted in a number of breakthroughs. Besides
M. J. Boschini   +13 more
doaj   +1 more source

High-density element concentrations in fish from subtidal to hadal zones of the Pacific Ocean

open access: yesHeliyon, 2018
Anthropogenic use of high density, toxic elements results in marine pollution which is bio-accumulating throughout marine food webs. While there have been several studies in various locations analyzing such elements in fish, few have investigated ...
Connor J. Welty   +3 more
doaj   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

open access: yesAdvanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang   +12 more
wiley   +1 more source

Emerging Materials and Future Strategies for Solid Oxide Electrochemical Cells

open access: yesAdvanced Energy Materials, EarlyView.
Solid oxide electrochemical cells operate under strongly coupled electrochemical and thermodynamic conditions, where performance is constrained by interactions among crystal structure, defect chemistry, and interfacial evolution. This review, based on a structure‐defect‐property‐durability framework, reveals the roles of lattice symmetry and defect ...
Qiuchun Lu   +4 more
wiley   +1 more source

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