Results 41 to 50 of about 6,088 (266)

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Chains on CR Manifolds and Lorentz Geometry [PDF]

open access: yesTransactions of the American Mathematical Society, 1988
We show that two nearby points of a strictly pseudoconvex CR manifold are joined by a chain. The proof uses techniques of Lorentzian geometry via a correspondence of Fefferman. The arguments also apply to more general systems of chain-like curves on CR manifolds.
openaire   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Modelling of the work processes high-pressure pump of common rail diesel injection system

open access: yesE3S Web of Conferences, 2016
Common rail injection systems are becoming a more widely used solution in the fuel systems of modern diesel engines. The main component and the characteristic feature of the system is rail injection of the fuel under high pressure, which is passed to the
Botwinska Katarzyna   +2 more
doaj   +1 more source

On normal CR-submanifolds of S-manifolds [PDF]

open access: yesColloquium Mathematicum, 1993
The notion of a CR-submanifold of an \(S\)-manifold was introduced by the reviewer [Stud. Cercet. Mat. 35, 127-136 (1983; Zbl 0516.53044)]. In the paper under review, the normality of such a submanifold is defined. Necessary and sufficient conditions for a CR-submanifold of an \(S\)- manifold to be normal are given.
Cabrerizo, José L.   +2 more
openaire   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Geometry of hypersurfaces of a quarter symmetric non metric connection in a quasi-Sasakian manifold

open access: yesKarpatsʹkì Matematičnì Publìkacìï, 2015
The purpose of the paper is to study the notion of CR-submanifold and the existence of some structures on a hypersurface of a quarter symmetric non metric connection in a quasi-Sasakian manifold.
Sh. Rahman
doaj   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur   +5 more
wiley   +1 more source

Regularization of Local CR-Automorphisms of Real-Analytic CR-Manifolds [PDF]

open access: yesJournal of Geometric Analysis, 2010
Let M be a connected generic real-analytic CR-submanifold of a finite-dimensional complex vector space E. Suppose that for every point a in M the Lie algebra hol(M,a) of germs of all infinitesimal real-analytic CR-automorphisms of M at a is finite-dimensional and its complexification contains all constant vector fields and the Euler vector field. Under
Isaev, Alexander, Kaup, W.
openaire   +4 more sources

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

open access: yesAdvanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice   +2 more
wiley   +1 more source

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