Results 141 to 150 of about 1,475,288 (355)
Language, listening and learning:critically reflective accountability for INGOs [PDF]
, 2013 Crack, Angela Maria
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
A nonlocal elasticity theory to model the static behaviour of edge-cracked nanobeams
Fracture and Structural IntegrityIn the present paper, the mechanical behaviour of edge-cracked nanobeams under Mixed-Mode loading is analytically investigated by means of the Stress-Driven nonlocal model. Firstly, the proposed formulation is outlined, and then applied to the case of a
Daniela Scorza +5 more
doaj +1 more source
Annular cracks in thin films of nanoparticle suspensions drying on a fiber
, 2013 We report an experimental study of the crack pattern formed during the drying of a colloidal suspension. A horizontal fiber, which provides a one dimensional, boundary-free substrate, is coated by a film of micronic thickness.
Boulogne, François +2 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Reversing the telescope:evaluating NGO peer regulation initiatives [PDF]
, 2016 Crack, Angela
core +1 more source
Crack propagation in thin shells by explicit dynamics solid-shell models [PDF]
, 2013 A computational technique for the simulation of crack propagation due to cutting in thin structures is proposed. The implementation of elastoplastic solid-shell elements in an explicit framework is discussed.
Pagani, Mara, Perego, Umberto
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The regulation of international NGOs:assessing the effectiveness of INGO Accountability Charter [PDF]
, 2018 Crack, Angela
core +1 more source