Results 121 to 130 of about 68,665 (303)

Finite element models for predicting crack growth characteristics in composite materials [PDF]

open access: yes
Two dimensional and quasi-three dimensional, linear elastic finite element models for the prediction of crack growth characteristics, including crack growth direction, in laminated composite materials are presented.
Buczek, M. B., Herakovich, C. T.
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

The mechanics of delamination in fiber-reinforced composite materials. Part 1: Stress singularities and solution structure [PDF]

open access: yes
The fundamental mechanics of delamination in fiber composite laminates is studied. Mathematical formulation of the problem is based on laminate anisotropic elasticity theory and interlaminar fracture mechanics concepts.
Choi, I., Wang, S. S.
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Crack closure of small fatigue cracks.

open access: yesTRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A, 1987
Keiro TOKAJI, takeshi OGAWA, Shuji OSAKO
openaire   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

On the interaction of ultrasound with cracks: Applications to fatigue crack growth [PDF]

open access: yes
Partial contact of two rough fatigue crack surfaces leads to transmission and diffraction of an acoustic signal at those contacts. Recent experimental and theoretical efforts to understand and quantify such contact in greater detail are discussed.
Buck, O.   +2 more
core   +1 more source

Partial crack closure under block loading [PDF]

open access: yes, 1980
Fatigue crack propagation tests under high-low and low-high block loading sequences have been performed in aluminium alloy specimens. The tests were carried out at constant [Delta]K conditions. Two stress ratios were analysed: R = 0.05 and R = 0.4. Crack
Borrego, L. P.   +2 more
core   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Composite interlaminar fracture toughness: Three-dimensional finite element modeling for mixed mode 1, 2 and 3 fracture [PDF]

open access: yes
A computational method/procedure is described which can be used to simulate individual and mixed mode interlaminar fracture progression in fiber composite laminates.
Chamis, C. C., Murthy, P. L. N.
core   +1 more source

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