Results 41 to 50 of about 9,188 (302)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Fatigue crack growth rates under variable amplitude load spectra containing tensile underloads [PDF]

, 2003
An extensive research program was performed to investigate the load interaction effect of the combined action of small amplitude high R ratio cycles and large amplitude low R ratio underloads on the crack growth of large cracks.
Zitounis, Vasilios
core  

Characterization of crack nucleation in TA6V under fretting-fatigue loading using the potential drop technique [PDF]

, 2010
Crack initiation in a Ti-6Al-4V alloy was investigated experimentally in fretting fatigue conditions. A cylinder-plane geometry was used for the contact, and partial slip conditions were considered.
Deyber, S., S. Deyber, Kubiak, KJ, J. Meriaux, Kubiak, Krzysztof, Fouvry, S, S. Fouvry, Meriaux, J., K.J. Kubiak, Meriaux, J, Deyber, S, Fouvry, S.   +11 more
core   +1 more source

Measurement and simulation of strain fields around crack tips under mixed-mode fatigue loading [PDF]

Fracture and Structural Integrity, 2015
For various configurations examined in a series of fatigue experiments on thin-walled tubes under tension and torsion, the experimental results – crack path, crack growth life, near crack tip deformations, and crack closure – are measured and compared to
Y. Hos, M. Vormwald, J.L.F. Freire
doaj   +2 more sources

An Improved Crack Breathing Model and Its Application in Crack Identification for Rotors

Machines, 2023
The crack breathing model and crack identification method for rotors using nonlinearity induced by cracks are studied in this work. Firstly, the finite element method is utilized to model a rotor–bearing system with a response-dependent breathing crack ...
Qi Liu, Shancheng Cao, Zhiwen Lu
doaj   +1 more source

Fatigue crack growth and crack closure in vacuum.

TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A, 1985
For S35C medium carbon steel and A5083-O aluminum alloy, fatigue crack growth tests were carried out in vacuum and in air under ΔK-increasing-decreasing condition, and crack growth rates and crack closure behavior were investigated in detail. In addition, ΔK constant tests were performed in air-to-vacuum-to-air environment.
m.jono, Song, JH Song, Ji Ho, m.ohgaki
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Fatigue Crack Growth Rate of the Long Term Operated Puddle Iron from the Eiffel Bridge

Metals, 2019
The paper summarises an experimental study on the fatigue crack propagation and cracks paths in ancient steel—19th-century puddle iron from the Eiffel bridge. The tests were performed with the load R-ratio equal to 0.05 and 0.5.
Grzegorz Lesiuk, José A. F. O. Correia, Michał Smolnicki, Abílio M. P. De Jesus, Monika Duda, Pedro A. Montenegro, Rui A. B. Calcada   +6 more
doaj   +1 more source

Full‐field characterization of a fatigue crack: Crack closure revisited [PDF]

Fatigue & Fracture of Engineering Materials & Structures, 2018
AbstractThe full‐field of a fatigue crack, ahead and behind the crack tip, has been examined in this work using Digital Image Correlation. We measured, in situ, the surface crack opening displacements at selected locations behind the crack tip and the evolution of the near‐tip displacements and strains ahead of the crack tip, during loading and ...
J. Tong, S. Alshammrei, T. Wigger, C. Lupton, J.R. Yates   +4 more
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source