Results 41 to 50 of about 186,782 (332)

Study on Fracture Behavior of GH4169 Superalloy Considering Crack Closure Effect: Combining Numerical Modeling and BSL 3D DIC

open access: yesApplied Sciences
As a critical aerospace structural material, the fatigue crack propagation behavior and fatigue life of the nickel-based GH4169 superalloy are directly related to the service safety of engineering components.
Zechang Li   +9 more
doaj   +1 more source

Experimental and Numerical Study on Crack Propagation of Cracked Plates under Low Cycle Fatigue Loads

open access: yesJournal of Marine Science and Engineering, 2023
The traditional study on fatigue strength for ship structures usually focuses on high cycle fatigue and ignores low cycle fatigue. However, given the recent trend towards large-scale ship development, the stress and deformation experienced by ship ...
Dong Qin, Xu Geng, Zhao Jie, Hu Yaoyu
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Fatigue crack growth rates under variable amplitude load spectra containing tensile underloads [PDF]

open access: yes, 2003
An extensive research program was performed to investigate the load interaction effect of the combined action of small amplitude high R ratio cycles and large amplitude low R ratio underloads on the crack growth of large cracks.
Zitounis, Vasilios
core  

Numerical simulation of fatigue crack propagation with plasticity-induced crack closure under different loading conditions (Development of direct numerical simulation using S-version FEM and simplified method)

open access: yesNihon Kikai Gakkai ronbunshu, 2019
This paper presents two numerical simulation methods for fatigue crack propagations with the plasticity-induced crack closure under arbitrary cyclic loading conditions.
Yuichi SHINTAKU   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Characterization of crack nucleation in TA6V under fretting-fatigue loading using the potential drop technique [PDF]

open access: yes, 2010
Crack initiation in a Ti-6Al-4V alloy was investigated experimentally in fretting fatigue conditions. A cylinder-plane geometry was used for the contact, and partial slip conditions were considered.
Deyber, S.   +11 more
core   +1 more source

Predicting creep-fatigue crack growth rates in Alloy 709 using finite element simulations of plasticity and creep-induced crack closure

open access: yesMATEC Web of Conferences, 2018
This paper reports on a computational study and experimental validation of creep-fatigue crack growth rates at high temperature in two structural materials.
Ramirez Jose   +6 more
doaj   +1 more source

Effects of crack closure and friction for linear crack under normal impact [PDF]

open access: yesEngineering Analysis with Boundary Elements, 2020
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Menshykov, Oleksandr   +2 more
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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