Results 51 to 60 of about 9,782,361 (275)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Numerical Simulation of the Effect of Pre-Strain on Fatigue Crack Growth in AA2024-T351

Metals
The objective here is to study the effect of pre-strain on fatigue crack growth (FCG) in 2024-T351 aluminum alloy. Three pre-strain conditions were considered: without pre-strain, compressive and tensile permanent pre-strains of 4%.
Diogo M. Neto, Edmundo Sérgio, André Agra, Fernando V. Antunes   +3 more
doaj   +1 more source

Effect of Crack Closure on Permeability in Abutment Pressure Area

Meikuang Anquan, 2020
The mechanical model of crack closure was established, and the zone of crack closure was calculated combining with the abutment pressure formula.
LI Li, YU Lei, ZHANG Shuangyu, KANG Qiang
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

An analytical workflow for predicting the stress dependency of the crack aperture and diameter based on the stress-dependent crack area

Frontiers in Earth Science
The patterns of crack closure are determined by the stress distribution on the crack surface. Generally, the crack closure model is characterized by the stress-dependency of the crack diameter.
Chenghao Cao, Chenghao Cao, Junhua Hu, Junhua Hu, Weihua Liu, Hao Liu, Songhui Li, Nazim Hussain   +7 more
doaj   +1 more source

Environmentally-assisted Fatigue Crack Growth in AA7050-T73511 Al Alloy and AA2050-T84 Al-Cu-Li Alloy [PDF]

Materials Research, 2015
The aim of this study was to evaluate and compare the effect of low temperature and saline environment on the fatigue crack growth behavior of the AA7050-T7451 Al alloy and the recently developed AA2050-T Al-Cu-Li alloy.
Jéferson Aparecido Moreto, Fernando Antônio Paschoal Júnior, Carla Isabel Santos Maciel, Luis Henrique Camargo Bonazzi, José Francisco Leonelli Júnior, Cassius Olívio Figueiredo Terra Ruchert, Waldek Wladimir Bose Filho   +6 more
doaj   +2 more sources

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

A Numerical Study of the Effect of Isotropic Hardening Parameters on Mode I Fatigue Crack Growth

Metals, 2020
The consideration of plastic crack tip opening displacement (CTOD, δp), as a crack driving force has given us the opportunity to predict fatigue crack growth (FCG) rate numerically, and, therefore, to develop parametric studies focused on the effect
M. F. Borges, F. V. Antunes, P. A. Prates, R. Branco   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

An Integral Formulation of Two-Parameter Fatigue Crack Growth Model

Advances in Materials Science and Engineering, 2018
A two-parameter fatigue crack growth algorithm in integral form is proposed, which can describe the continuous crack growth process over the time period.
Jianguo Wu, Shan Jiang, Wei Zhang, Zili Wang   +3 more
doaj   +1 more source