Results 131 to 140 of about 356,136 (229)

Synthesis of Nitrogen‐Containing Heterocyclic Scaffolds and Applications in Scaffold Hopping: Development of an Aripiprazole Analog

ChemMedChem, Volume 21, Issue 20, 28 October 2026.
A series of 12 novel fused [6,6] saturated and unsaturated nitrogen bicycles is synthesized in three to five steps and expands the CRAFT library's fragment space. A 2,6‐naphthyridin‐3‐ol core replaces the dihydroquinolinone scaffold of aripiprazole, a scaffold‐hopping strategy.
Temitayo Omowumi Alegbejo Price, Pieterjan Winant, Paulo Eliandro da Silva Júnior, Shaiani Maria Gil de Melo, Pedro Henrique Gobira, Julia Possamai Gimenes, Pedro Tenório Teixeira Fernandes Leite, Vinícius Gonçalves Maltarollo, Gustavo Henrique Goulart Trossini, A. Ganesan, Sâmia Regiane Lourenço Joca, Wim Dehaen, Flavio da Silva Emery   +12 more
wiley   +1 more source

Lung Herniation Associated With Crack Cocaine Use: An Uncommon Cause of Chest Pain. [PDF]

Cureus, 2022
Nogueira Gomes T, Camelo Pereira M, Smith SC, Melgar TA.   +3 more
europepmc   +1 more source

Crack and powder cocaine federal legislation: A sentencing disparity and potential for policy improvement

, 2009
Since its introduction into the United States in the 1980s, crack cocaine has been a harsh epidemic that has taken its toll on a countless number of people.
Segal, Zubin
core   +1 more source

Guns and Trafficking in Crack-Cocaine and Other Drug Markets

, 2011
This article examines the relationship between gun possession and the nature of an offender’s involvement in drug markets. The analyses are based on data obtained from drug offenders who participated in the 1997 Survey of Inmates of State and Federal ...
Luke Bonkiewicz, Richard B. Felson
core   +1 more source

Syphilis and Co-Infections with HIV-1, HBV, and HCV among People Who Use Crack-Cocaine in Northern Brazil. [PDF]

Pathogens, 2022
Baia KLN, Cordeiro ACC, Frade PCR, Gouveia AGN, Resque RL, Pinheiro LML, Fonseca RRS, Machado LFA, Martins LC, Kupek E, Fischer B, Oliveira-Filho AB.   +11 more
europepmc   +1 more source

An Empirical Analysis of Imprisoning Drug Offenders [PDF]

The number of prisoners incarcerated on drug-related offenses rose fifteen-fold between 1980 and 2000. This paper provides the first systematic empirical analysis of the implications of that dramatic shift in public policy.
Ilyana Kuziemko, Steven D. Levitt
core  

Connecticut and federal penalties for crack and cocaine

, 1999
"June 2, 1999."; Discusses Connecticut and federal law on crack and ...
Reinhart, Christopher,
core  

THE COMPARISON OF SEXUAL BEHAVIOR HIGH RISK SEXUAL BEHAVIOUR AND SELF-HARM BEHAVIOUR IN STIMULANTS/NARCOTIC SUBSTANCE ABUSE

Research on Addiction, 2009
THE HYPOTHESIS, This survey compares the sexual behavior, the high risk sexual behavior and self-harm behavior of narcotic substance users (opium, crack, and heroin) with stimulants substance uses (ice, cocaine).
Lale Mirsoleimani, Bagher Sanaee zaker, Shahram Vaziri,   +3 more
doaj  

Childhood trauma subtypes may influence the pattern of substance use and preferential substance in men with alcohol and/or crack-cocaine addiction. [PDF]

Braz J Psychiatry, 2022
Hoffmann A, Benzano D, Ornell F, Kessler FHP, von Diemen L, Schuch JB.   +5 more
europepmc   +1 more source

A cultural and political difference: comparing the racial and social framing of population crack cocaine use between the United States and France. [PDF]

Harm Reduct J, 2022
Goulian A, Jauffret-Roustide M, Dambélé S, Singh R, Fullilove RE.   +4 more
europepmc   +1 more source