By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Crack image detection based on fractional differential and fractal dimension
In civil engineering, crack detection using image processing has gained much attention among researchers and transportation agencies. As the crack image often presents a fuzzy boundary and random shape, it is difficult to achieve satisfactory detection ...
Ting Cao +3 more
doaj +1 more source
Comparison of the crack pattern in accelerated corrosion tests and in finite elements simulations [PDF]
In this work, the crack pattern obtained in accelerated corrosion tests is compared to the one obtained in numerical simulations for reinforced steel concrete samples.
Planas Rosselló, Jaime +2 more
core +1 more source
Vibration-based damage detection in an aircraft wing scaled model using principal component analysis and pattern recognition [PDF]
This study deals with vibration-based fault detection in structures and suggests a viable methodology based on principal component analysis (PCA) and a simple pattern recognition (PR) method. The frequency response functions (FRFs) of the healthy and the
Cartmell, Matthew +3 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Quantitative Detection of Cracks in Steel Using Eddy Current Pulsed Thermography
Small cracks are common defects in steel and often lead to catastrophic accidents in industrial applications. Various nondestructive testing methods have been investigated for crack detection; however, most current methods focus on qualitative crack ...
Zhanqun Shi +4 more
doaj +1 more source
An improved U-Net model for concrete crack detection
Crack detection plays an important role in disease assessment of concrete buildings. However, factors such as complex background, irregular edge, and the real-time and accuracy requirement also make crack detection a challenging task. Aiming at the above
Chenglong Yu +4 more
doaj +1 more source
Lamb wave near field enhancements for surface breaking defects in plates [PDF]
Near field surface wave ultrasonic enhancements have previously been used to detect surface breaking defects in thick samples using Rayleigh waves. Here, we present analogous surface wave enhancements for Lamb waves propagating in plates.
Clough, A. R. +1 more
core +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source

