Results 51 to 60 of about 230,446 (308)

Finite element analyses of fatigue crack growth under small scale yielding conditions modelled with a cyclic cohesive zone approach [PDF]

, 2013
Mode I fatigue crack growth is modelled and investigated with a cohesive zone approach. A 2D finite element boundary layer model under plane strain and small scale yielding conditions is used to generate fatigue crack growth rate curves ...
Kuna, Meinhard, Roth, Stephan
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Fatigue crack growth of cast austenitic stainless steels

工程科学学报, 2015
The influences of stress ratio, single overload and high-low loading sequence on the fatigue crack growth of Z3CN20-09M cast austenitic stainless steels were studied with compact tension specimens. When the stress intensity factor range is identical, the
LU: Xu-ming, LI Shi-lei, WANG Xi-tao, WANG Yan-li   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Fatigue and Crack Growth under Constant- and Variable-Amplitude Loading in 9310 Steel Using “Rainflow-on-the-Fly” Methodology

Metals, 2021
Fatigue of materials, like alloys, is basically fatigue-crack growth in small cracks nucleating and growing from micro-structural features, such as inclusions and voids, or at micro-machining marks, and large cracks growing to failure.
James C. Newman
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Microstructural modelling of creep crack growth from a blunted crack [PDF]

, 1998
The effect of crack tip blunting on the initial stages of creep crack growth is investigated by means of a planar microstructural model in which grains are represented discretely. The actual linking-up process of discrete microcracks with the macroscopic
Giessen, E. van der,, Onck, P.R.,
core  

An experimental study of residual stress and direction-dependence of fatigue crack growth behaviour in as-built and stress-relieved selective-laser-melted Ti6Al4V [PDF]

, 2019
Selective-laser-melting (SLM) is a powder-bed fusion additive-manufacturing process that has the potential to deliver three-dimensional complex parts with mechanical properties comparable or superior to parts produced via traditional manufacturing using ...
Abdul Khadar Syed, Abd‐Elghany, Bilal Ahmad, Cain, Carter, David Eatock, de Formanoir, Dutta, Edwards, Edwards, Facchini, Galarraga, Gong, Harrison, Hrabe, Hua Guo, Jonathan Meyer, Kobryn, Kobryn, Kruth, Liu, Louvis, Mercelis, Michael E. Fitzpatrick, Nickel, Olakanmi, Parry, Prime, Qian, Qiu, Rangaswamy, Safdar, Santisteban, Simonelli, Simonelli, Stock, Tammas-Williams, Thays Machry, Thijs, Thijs, Van Hooreweder, Vilaro, Vrancken, Vrancken, Vrancken, Vrancken, Vydehi Arun Joshi, Wan, Wu, Xiang Zhang, Xu, Yang, Yang, Zaeh, Zhai, Zhang   +55 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source