Results 131 to 140 of about 42,379 (316)

Determining the Role of Acicular Ferrite Carbides in Cleavage Fracture Crack Initiation for Two Medium Carbon Microalloyed Steels. [PDF]

Materials (Basel), 2023
Jovanović G, Glišić D, Dikić S, Međo B, Marković B, Vuković N, Radović N.   +6 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Prediction of Fatigue Crack Initiation of 7075 Aluminum Alloy by Crystal Plasticity Simulation. [PDF]

Materials (Basel), 2023
Shiraiwa T, Briffod F, Enoki M.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Experimental Research on the Propagation Mode of 3D Hollow Cracks and Material Strength Characteristics Under Hydro-Mechanical Coupling

Journal of Marine Science and Engineering
The fracture evolution and the strength characteristics of a jointed rock mass under hydro-mechanical coupling are key issues that affect the safety and stability of underground engineering.
Bangxiang Li, Guanhua Wang, Dongyang Xu, Hongbo Zhao   +3 more
doaj   +1 more source

Study on the Fatigue Crack Initiation and Growth Behavior in Bismuth- and Lead-Based Free-Cutting Brasses. [PDF]

Materials (Basel), 2022
Masuda K, Ishihara S, Oguma N, Ishiguro M, Sakamoto Y, Iwasaki M.   +5 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Combined Crack Initiation and Crack Growth Model for Multi-Layer Polymer Materials. [PDF]

Materials (Basel), 2022
Pletz M, Arbeiter FJ.
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Predicting crack initiation due to ratchetting in rail heads using critical element analysis

, 2013
This paper presents a strategy to predict the lifetime of rails subjected to large rolling contact loads that induce ratchetting strains in the rail head.
Hargreaves, Douglas, Wickramasinghe, Isuru Udara, De Pellegrin, Dennis   +2 more
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