Results 131 to 140 of about 2,476,755 (297)

EXPERIMENTAL AND THEORETICAL INVESTIGATIONS ON MODE I CRACK PROPAGATION IN NOTCHES UNDER CYCLIC LOADING [PDF]

open access: yes, 2007
Research works regarding crack opening stresses covering various types of Mode I cracks initiated and growing in notches under cyclic loading are shown. A large number of parameters influence the crack opening behavior, i.e. material, crack length, notch
Georgios SAVAIDIS   +7 more
core   +2 more sources

Investigation Of Mode Ii Crack Growth Following A Very High Speed Impact

open access: yes, 2008
A recoverable plate impact testing technology has been developed for studying fracture mechanisms of mode II crack. With this technology, a single duration stress pulse with submicrosecond duration and high loading rates, up to 10(8) MPam(1/2)s(-1), can ...
Ma W(马维)   +2 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

OS12W0373 Crack growth mechanism and crack size dependency of Mode II and Mode III fatigue crack threshold

open access: yesThe Abstracts of ATEM : International Conference on Advanced Technology in Experimental Mechanics : Asian Conference on Experimental Mechanics, 2003
Toyama, Kyohei   +2 more
openaire   +1 more source

Mode I+II Fatigue Crack Growth Delay by Stop-Holes

open access: yesJournal of Aerospace Technology and Management, 2018
The technique of retarding the growth of fatigue cracks by drilling holes on the crack tip is well known. Most of the research works on this subject are limited to fatigue cracks subjected to mode I loading conditions.
Dimitrios G. Pavlou
doaj  

Effect of flaw inclination angle and crack arrest holes on mechanical behavior and failure mechanism of pre-cracked granite under uniaxial compression

open access: yesApplied Rheology
In order to investigate the impact of flaw inclination angles (FA) and crack arrest holes on the mechanical characteristics and failure modes of combined pre-cracked granite, uniaxial compression simulation tests were conducted on specimens with ...
Li Yanzhang   +3 more
doaj   +1 more source

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