Results 41 to 50 of about 71,141 (311)

Fatigue damage evaluation of 316LN stainless steel using acoustic emission monitoring

open access: yes工程科学学报, 2018
The initiation and growth of fatigue cracks usually lead to serious fatigue failure of steel structures such as pressure vessels and pipelines. Therefore, for the safety and reliability of engineering structures, monitoring the fatigue crack growth and ...
ZHANG Jin   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Bibliometric Analysis and Review of Deep Learning-Based Crack Detection Literature Published between 2010 and 2022

open access: yesBuildings, 2022
The use of deep learning (DL) in civil inspection, especially in crack detection, has increased over the past years to ensure long-term structural safety and integrity.
Luqman Ali   +4 more
doaj   +1 more source

Continued Field Evaluation of Precutting for Maintaining Asphalt Concrete Pavements with Thermal Cracking [PDF]

open access: yes, 2017
In continuation of a previously completed project entitled Evaluate Presawn Transverse Thermal Cracks for Asphalt Concrete Pavement, this project was a further effort to understand important variables in the thermal cracking process through continued ...
Liu, Jenny   +2 more
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Thermal imagery temperature gradient analysis through deformable transformer residual regression network for crack severity estimation

open access: yesApplications in Engineering Science
Structural crack severity estimation is critical for preventive maintenance, yet conventional approaches often fall short in capturing subsurface defects from thermal imagery due to noise and irrelevant metadata.
Shyamala Devi M   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Investigation of asphalt pavement crack propagation based on micromechanical finite element: A case study

open access: yesCase Studies in Construction Materials, 2023
Cracking is a prevalent issue in expressway pavements in Shanxi Province, exhibiting various types. Based on field investigations, the primary types of asphalt pavement cracks observed in Shanxi expressways can be categorized as top-down crack (TDC ...
Xu Xia   +5 more
doaj   +1 more source

EVALUATION PAVEMENT DISTRESSES USING PAVEMENT CONDITION INDEX [PDF]

open access: yes, 2011
Pavement deterioration is resulted by both environmental and structural causes. It is difficult to maintain the road on the same specification that was owned at the opening and problems start to appear represented in the pavement cracks, holes and ...
kushardjoko, wahyudi   +2 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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