Results 51 to 60 of about 30,771 (303)
Analytical solution of the stress field and plastic zone at the tip of a closed crack
Frontiers in Earth ScienceThe investigation of stress field and plastic zone distribution at the closed crack tip provides a fundamental basis for failure analysis and life prediction of geotechnical materials. Closed crack is a common crack in geotechnical materials.
Guanzhong Wu +6 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Three-dimensional crack growth in multi-layered architectures for automotive plain bearings [PDF]
, 2009 The assessment of shielding and anti-shielding effects on crack growth in multi-layered architectures is achieved using elasto-plastic finite element models.
Burke-Veliz, A. +2 more
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Dislocations emission and crack extension at the atomistic crack tip in body-centered-cubic metal Mo [PDF]
, 1999 The behaviors of a crack in body-centered-cubic metal Mo under different loading modes were studied using the molecular dynamics method. Dislocation emission was observed near the crack tip in response to mode II loading with theta = 0 degrees in which ...
Tang, QH (reprint author), Chinese Acad Sci, LNM Inst Mech, Beijing 100080, Peoples R China. +2 more
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Jixie qiangdu, 2019 In this article, three dimensional elastic-plastic curved crack tip opening displacement under quasi-static loads has been mainly studied, and three dimensional curved crack tip opening displacement has been calculated as a practical application of a ...
YANG DaPeng +4 more
doaj
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Transient effect on ideally plastic stationary crack-tip fields [PDF]
, 1996 This paper analyses the transient effect on ideally plastic stationary crack-tip fields under mode I plane strain conditions, when the inertial forces are not negligible.
LI, XP (reprint author), ACAD SINICA,INST MECH,BEIJING 100080,PEOPLES R CHINA. +2 more
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Assessment of foam fracture in sandwich beams using thermoelastic stress analysis [PDF]
, 2009 Thermoelastic Stress Analysis (TSA) has been well established for determining crack-tip parameters in metallic materials. This paper examines its ability to determine accurately the crack-tip parameters for PVC foam used in sandwich ...
Mettemberg, C. +2 more
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Study on Crack Tip Temperature Field and Microstructure Damage for Wind Turbine Composite Blade
发电技术, 2019 The crack tip temperature field of blade with micro-defect based on the thermo-mechanical was studied. The microstructure damage mode of specimen fracture was proposed. The numerical model of the crack tip temperature field was established by the plastic
Linlin WANG +5 more
doaj +1 more source