Results 191 to 200 of about 3,613 (259)

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

Sediment heterogeneity affects navigation by burrowers: a modelling study. [PDF]

J R Soc Interface
Wang X, Rojas M, Dorgan K, Louhghalam A.
europepmc   +1 more source

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

Advanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang, Xinyan Sun, Yingchao Sun, Zeqiang Cheng, Zixiang Cheng, Shengbo Han, Ying Feng, Wenbo Yang, Huimin Li, Meichen Zhu, Xiaoling Wu, Jinghua Zhang, Jihua Tang, Honglian Li, Yanyong Cao, Canxing Duan, Yan Shi   +16 more
wiley   +1 more source

Graphene Nanofiller Type Matters: Comparative Analysis of Static and Fatigue Delamination Resistance in Modified Carbon Fiber Composites. [PDF]

Polymers (Basel)
Zafeiropoulou K, Kostagiannakopoulou C, Sotiriadis G, Kostopoulos V.   +3 more
europepmc   +1 more source

ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T. Rosen, Yingyu Wang, Chun‐Wei D. Chen, Cheng Zhang, Mingye Feng   +12 more
wiley   +1 more source

Theoretical and simulation analysis of a rectangular crack in the piezoelectric material. [PDF]

Sci Rep
Zhang Y, Li J.
europepmc   +1 more source

Experimental Study on the Mechanical Properties and Fracture Evolution Laws of Multifractured Sandstone under Saturated Water Conditions. [PDF]

ACS Omega
Yang M, Mu L, Guo M.
europepmc   +1 more source

Experimentally validated finite element model for mechanical and fracture characteristics of SiCN thin films under different loads. [PDF]

Sci Rep
Kumar D, Meena RK, Hirshikesh, Ghadai RK.   +3 more
europepmc   +1 more source

Interface Rotation in Accumulative Rolling Bonding (ARB) Cu/Nb Nanolaminates Under Constrained and Unconstrained Loading Conditions as Revealed by In Situ Micromechanical Testing. [PDF]

Nanomaterials (Basel)
Sahay R, Radchenko I, Ananthasubramanian P, Harito C, Briffod F, Yasuda K, Shiraiwa T, Jhon M, Speaks R, Speaks D, Lee K, Enoki M, Raghavan N, Budiman AS.   +13 more
europepmc   +1 more source