Results 31 to 40 of about 3,613 (259)

Influence of the process of damage accumulation on the asymptotic behavior of stress fields under creep conditions of a sample with a central crack

Вестник Самарского университета: Естественнонаучная серия, 2023
The present study describes the influence of the mutual effect of damage accumulation on the stress fields at the central crack tip in the plate subjected to uniaxial tension.
Yulia S. Bykova, Larisa V. Stepanova
doaj   +1 more source

Experimental Investigation of Crack Propagation and Strain Fields Evolution around a Crack Tip in 5A05 Aluminum Alloy

Metals, 2018
In situ scanning electron microscopy three-point bending test was employed in this study to investigate the crack initiation and propagation in 5A05 aluminum alloy.
Jijun Li, Wencai Li, Chunwang Zhao, Yongming Xing, Fengchao Lang, Xiaohu Hou   +5 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Identification of the plastic zone using digital image correlation [PDF]

Fracture and Structural Integrity, 2014
In this paper Digital Image Correlation (DIC) is used to study the evolution of the plastic zone close to a crack tip. A modified CT-specimen was used in order to fulfill the plane stress condition.
M. Rossi, M. Sasso, G. Chiappini, E. Mancini, D. Amodio   +4 more
doaj   +3 more sources

Research on hydrogen induced cracking behavior and service performance of metal pipeline material

Frontiers in Materials
This study systematically investigates the fracture behavior of X80 pipeline steel welded joints under hydrogen-induced cracking (HIC) conditions through combined experimental characterization and numerical simulation.
Yongjun Jia, Yongjun Jia, He Xue, Zheng Wang   +3 more
doaj   +1 more source

Characterisation of crack tip fields under non-uniform fatigue loading [PDF]

Fracture and Structural Integrity, 2013
The paper analyses previously reported work, which uses digital image correlation to measure fatigue crack closure. As well as determining crack opening loads, the information on crack shape may be used to estimate the stress intensity factor, as well as
D. Nowell, M.E. Kartal, P.F.P. de Matos
doaj   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Multiparametric presentation of the crack-tip fields in the vicinity of longitudinal shear crack

Вестник Самарского университета: Естественнонаучная серия
The article is devoted to the study of the stress field at the tip of a longitudinal shear crack based on a multiparametric asymptotic representation of the stress field at the crack tip in a linearly elastic isotropic material.
Yulia N. Bakhareva
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source