Results 31 to 40 of about 3,593 (294)
Effect of crack closure on non-linear crack tip parameters [PDF]
, 2015 Crack closure concept has been widely used to explain different issues of fatigue crack propagation. However, some authors have questioned the relevance of crack closure and have proposed alternative concepts.
Sousa, T. +4 more
core +1 more source
Materials Research Express, 2023 The cryogenic fracture toughness of the SA645/304L dissimilar weld, produced using continuous wave IPG fiber laser welding with a 0.3 mm beam offset towards the 304L side, and the microstructural effects on the fracture behavior were systematically ...
Fei Zhou +6 more
doaj +1 more source
International Journal of Applied Mechanics and Engineering, 2020 The paper presents a comprehensive analysis of the stress field and selected triaxiality parameters near the crack tip for C(T) specimen dominated by the plane strain state using the finite element method.
M. Graba
doaj +1 more source
, 2015 In this paper, the correlation of the cyclic J-integral, ΔJ, and the cyclic crack-tip opening displacement, ΔCTOD, is studied in the presence of crack closure to assess the question if ΔJ describes the crack-tip opening displacement in this case. To this
Metzger, M. +5 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Fatigue crack growth rates under variable amplitude load spectra containing tensile underloads [PDF]
, 2003 An extensive research program was performed to investigate the load interaction effect of the combined action of small amplitude high R ratio cycles and large amplitude low R ratio underloads on the crack growth of large cracks.
Zitounis, Vasilios
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Silva Fennica, 2004 Stress intensity factor of radiata pine (Pinus radiata) in Tangential-Longitudinal opening mode was determined from crack-tip displacement fields obtained from digital image correlation in conjunction with orthotropic fracture theory. For lower loads,
Samarasinghe, Sandhya, Kulasiri, Don
doaj +1 more source
A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions
Advanced Engineering Materials, EarlyView.This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice +2 more
wiley +1 more source