Results 111 to 120 of about 1,119 (244)

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

open access: yesiMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu   +7 more
wiley   +1 more source

Fracture and Fatigue Assessment of Bonded Composite Patch Repairs in Notched and Cracked Plates. [PDF]

open access: yesPolymers (Basel)
Beylergil B   +6 more
europepmc   +1 more source

Laparoscopic Methylene Blue Photodynamic Therapy for Intraabdominal Infection: A Preclinical Feasibility Study in a Rabbit Model of Perforated Appendicitis

open access: yesLasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives Perforated appendicitis commonly results in intra‐abdominal infection requiring prolonged antibiotic therapy. Intraoperative antimicrobial adjuncts are limited, and photodynamic therapy (PDT) may provide a targeted, resistance‐independent approach.
Timothy M. Baran   +7 more
wiley   +1 more source

Hydrogen‐Enhanced Stress Corrosion Cracking of Wire Arc Additive Manufactured Inconel 625 Superalloy in NaCl Solution: Mechanism of Synergistic Degradation

open access: yesMaterials and Corrosion, EarlyView.
Hydrogen‐enhanced SCC of WAAM Inconel 625 in 3.5 wt.% NaCl solution. Hydrogen charging reduces passive film stability (lower corrosion potential) and promotes pitting at Laves phase/matrix interfaces. Stress corrosion cracks propagate along Laves‐rich regions, leading to quasi‐cleavage brittle fracture.
Xu Zhang   +5 more
wiley   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu   +2 more
wiley   +1 more source

Recycled Polyacrylonitrile Nanofiber Interleaves With Graphene Nanoplatelets for Adhesively Bonded Composite Joints: Lap‐Shear and Opening‐Mode Fracture Performance

open access: yesPolymer Composites, EarlyView.
Textile‐waste Orlon is transformed into recycled PAN nanofiber interleaves for tougher and more damage‐resistant adhesive bondlines. ABSTRACT This study presents a sustainable toughening strategy for adhesively bonded CFRP joints by using electrospun polyacrylonitrile (PAN) nanofiber interleaves produced from virgin PAN (vPAN) and recycled PAN (rPAN ...
Mehmet Emin Çetin   +3 more
wiley   +1 more source

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