Results 21 to 30 of about 496,309 (246)

Metformin pretreatment rescues olfactory memory associated with subependymal zone neurogenesis in a juvenile model of cranial irradiation

open access: yesCell Reports Medicine, 2021
Summary: Cranial irradiation (IR) is an effective adjuvant therapy in the treatment of childhood brain tumors but results in long-lasting cognitive deficits associated with impaired neurogenesis, as evidenced in rodent models. Metformin has been shown to
Daniel Derkach   +5 more
doaj   +1 more source

Post-radiation complications in children with acute lymphoblastic leukemia who underwent a course of cranial radiation

open access: yesЮжно-Российский онкологический журнал, 2022
Purpose of the study. To analyze the physical and neuropsychiatric development of pediatric patients who underwent cranial irradiation in the period from 2015 to 2020 in the radiotherapy department of the National Research Center of Oncology and to ...
T. S. Rogova   +8 more
doaj   +1 more source

Prediction Models for Radiation-Induced Neurocognitive Decline in Adult Patients With Primary or Secondary Brain Tumors: A Systematic Review

open access: yesFrontiers in Psychology, 2022
PurposeAlthough an increasing body of literature suggests a relationship between brain irradiation and deterioration of neurocognitive function, it remains as the standard therapeutic and prophylactic modality in patients with brain tumors.
Fariba Tohidinezhad   +8 more
doaj   +1 more source

Stroke as Late Sequela of Cranial Irradiation

open access: yesPediatric Neurology Briefs, 1991
The development of cerebrovascular disease manifested by strokes or transient ischemic attacks six months to four years after treatment of brain tumors in 11 children is reported from the Children’s Hospital of Los Angeles, University of Southern ...
J Gordon Millichap
doaj   +1 more source

The Abscopal Effects of Cranial Irradiation Induce Testicular Damage in Mice

open access: yesFrontiers in Physiology, 2021
To investigate whether the abscopal effects of cranial irradiation (C-irradiation) cause testicular damage in mice, male C57BL/6 mice (9weeks of age) were randomly divided into a sham irradiation group, a shielded group and a C-irradiation group and ...
Ling Guo   +18 more
doaj   +1 more source

Hypothyroidism due to Cranial and Craniospinal Irradiation

open access: yesКлиническая и экспериментальная тиреоидология, 2013
Благодаря успехам современной онкологии общая пятилетняя выживаемость при онкологических заболеваниях у детей и подростков составляет в целом 75% [4]. Большой вклад в эти достижения привнесло применение лучевой терапии (ЛТ) в составе комплексного лечения

doaj   +1 more source

Prophylactic cranial irradiation in extensive small-cell lung cancer

open access: yes, 2007
Background We conducted a randomized trial of prophylactic cranial irradiation in patients with extensive small-cell lung cancer who had had a response to chemotherapy.
Slotman, Ben   +9 more
core   +2 more sources

Neurocognitive and neuroanatomical changes in children with acute lymphoblastic leukemia treated with the modified BFM-95 protocol

open access: yesIndian Journal of Medical and Paediatric Oncology, 2019
Background: The use of cranial radiotherapy for central nervous system (CNS) prophylaxis in children with acute lymphoblastic leukemia (ALL) is debated owing to its effect on neurocognitive functioning, as only
Sundaramoorthy Chidambaram   +4 more
doaj   +1 more source

Olfactory Memory Impairment Differs by Sex in a Rodent Model of Pediatric Radiotherapy

open access: yesFrontiers in Behavioral Neuroscience, 2018
Although an effective treatment for pediatric brain tumors, cranial radiation therapy (CRT) damages surrounding healthy tissue, thereby disrupting brain development. Animal models of pediatric CRT have primarily relied on visual tasks to assess cognitive
Emma C. Perez   +9 more
doaj   +1 more source

Toxic Epidermal Necrolysis Associated with Antiepileptic Drugs and Cranial Radiation Therapy

open access: yesCase Reports in Oncological Medicine, 2013
Case reports on the development of toxic epidermal necrolysis (TEN) associated with concurrent administration of phenytoin with cranial radiation therapy (Ahmed (2004), Criton et al. (1997), and Rzany et al. (1996)), but reports about erythema multiforme,
Shereen Elazzazy   +3 more
doaj   +1 more source

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