Results 21 to 30 of about 496,309 (246)
Summary: Cranial irradiation (IR) is an effective adjuvant therapy in the treatment of childhood brain tumors but results in long-lasting cognitive deficits associated with impaired neurogenesis, as evidenced in rodent models. Metformin has been shown to
Daniel Derkach +5 more
doaj +1 more source
Purpose of the study. To analyze the physical and neuropsychiatric development of pediatric patients who underwent cranial irradiation in the period from 2015 to 2020 in the radiotherapy department of the National Research Center of Oncology and to ...
T. S. Rogova +8 more
doaj +1 more source
PurposeAlthough an increasing body of literature suggests a relationship between brain irradiation and deterioration of neurocognitive function, it remains as the standard therapeutic and prophylactic modality in patients with brain tumors.
Fariba Tohidinezhad +8 more
doaj +1 more source
Stroke as Late Sequela of Cranial Irradiation
The development of cerebrovascular disease manifested by strokes or transient ischemic attacks six months to four years after treatment of brain tumors in 11 children is reported from the Children’s Hospital of Los Angeles, University of Southern ...
J Gordon Millichap
doaj +1 more source
The Abscopal Effects of Cranial Irradiation Induce Testicular Damage in Mice
To investigate whether the abscopal effects of cranial irradiation (C-irradiation) cause testicular damage in mice, male C57BL/6 mice (9weeks of age) were randomly divided into a sham irradiation group, a shielded group and a C-irradiation group and ...
Ling Guo +18 more
doaj +1 more source
Hypothyroidism due to Cranial and Craniospinal Irradiation
Благодаря успехам современной онкологии общая пятилетняя выживаемость при онкологических заболеваниях у детей и подростков составляет в целом 75% [4]. Большой вклад в эти достижения привнесло применение лучевой терапии (ЛТ) в составе комплексного лечения
doaj +1 more source
Prophylactic cranial irradiation in extensive small-cell lung cancer
Background We conducted a randomized trial of prophylactic cranial irradiation in patients with extensive small-cell lung cancer who had had a response to chemotherapy.
Slotman, Ben +9 more
core +2 more sources
Background: The use of cranial radiotherapy for central nervous system (CNS) prophylaxis in children with acute lymphoblastic leukemia (ALL) is debated owing to its effect on neurocognitive functioning, as only
Sundaramoorthy Chidambaram +4 more
doaj +1 more source
Olfactory Memory Impairment Differs by Sex in a Rodent Model of Pediatric Radiotherapy
Although an effective treatment for pediatric brain tumors, cranial radiation therapy (CRT) damages surrounding healthy tissue, thereby disrupting brain development. Animal models of pediatric CRT have primarily relied on visual tasks to assess cognitive
Emma C. Perez +9 more
doaj +1 more source
Toxic Epidermal Necrolysis Associated with Antiepileptic Drugs and Cranial Radiation Therapy
Case reports on the development of toxic epidermal necrolysis (TEN) associated with concurrent administration of phenytoin with cranial radiation therapy (Ahmed (2004), Criton et al. (1997), and Rzany et al. (1996)), but reports about erythema multiforme,
Shereen Elazzazy +3 more
doaj +1 more source

