Results 81 to 90 of about 18,979 (223)

Automated surgical planning in spring-assisted sagittal craniosynostosis correction using finite element analysis and machine learning.

PLoS ONE, 2023
Sagittal synostosis is a condition caused by the fused sagittal suture and results in a narrowed skull in infants. Spring-assisted cranioplasty is a correction technique used to expand skulls with sagittal craniosynostosis by placing compressed springs ...
Jenson Jacob, Selim Bozkurt
doaj   +1 more source

Data‐Driven Insights into Hyperkinetic Disorders in Neurodevelopmental Syndromes and Epileptic Encephalopathies

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Childhood‐onset hyperkinetic movement disorders occur in a range of genetic conditions. Recently, there has been an increase in recognition of hyperkinetic movement disorders, mainly dystonia, chorea and dyskinesia, with monogenic conditions associated with neurodevelopmental delay (NDD) and also with developmental and epileptic ...
Hugo Morales‐Briceño, Shekeeb S. Mohammad, Rajeshwar Reddy Angiti, Velda Han, Michel Tchan, Russell C. Dale, Victor S.C. Fung   +6 more
wiley   +1 more source

Frontofacial Features of Unilateral Lambdoid Craniosynostosis: A Multicenter Assessment

Plastic and Reconstructive Surgery, Global Open, 2023
Background:. Unilateral lambdoid craniosynostosis is differentiated from deformational plagiocephaly primarily by assessing the cranium from posterior and bird’s-eye views.
Jonathan Lee, MD, Sanjay Naran, MD, Daniel Mazzaferro, MD, Ari Wes, MD, Erin E. Anstadt, MD, Jesse Taylor, MD, Jesse Goldstein, MD, Scott Bartlett, MD, Joseph Losee, MD   +8 more
doaj   +1 more source

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

Medicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti, Camilla Tavani, Elena Somenza, Nicolas Tassone, Antonio d'Amati, Marta Turati, Roberto Ronca   +6 more
wiley   +1 more source

The management of perioperative pain in craniosynostosis repair: a systematic literature review of the current practices and guidelines for the future

Maxillofacial Plastic and Reconstructive Surgery, 2022
Background Craniosynostosis is a condition characterized by a premature fusion of one or more cranial sutures. The surgical repair of craniosynostosis causes significant pain for the child.
Hatan Mortada, Raghad AlKhashan, Nawaf Alhindi, Haifa B. AlWaily, Ghada A. Alsadhan, Saad Alrobaiea, Khalid Arab   +6 more
doaj   +1 more source

A Possible Case of Temporomandibular Joint Dislocation, Trepanation, and Metabolic Bone Disease in a Young Adolescent From North‐Central Myanmar (1000–700 bce)

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT This osteobiography explores the life history of an adolescent who lived during the early‐mid Bronze Age (c. 1000–700 bce) and was buried at Nyaung'gan, a site in north‐central Myanmar. Burial 3b had multiple skeletal lesions, and their bones were covered in well‐remodeled subperiosteal new bone.
Anna Willis, Baptiste Pradier, Thu Thu Win, T. O. Pryce   +3 more
wiley   +1 more source

Craniosynostosis - Recognition, clinical characteristics, and treatment.

Bosnian Journal of Basic Medical Sciences, 2017
Craniosynostosis is a developmental craniofacial anomaly, resulting in impairment of brain development and abnormally shaped skull. The main cause of craniosynostosis is premature closure of one or more cranial sutures.
N. Kajdič, P. Spazzapan, T. Velnar
semanticscholar   +1 more source

Multidisciplinary care of craniosynostosis

Journal of Multidisciplinary Healthcare, 2017
Edward P Buchanan,1 Yunfeng Xue,1 Amy S Xue,1 Asaf Olshinka,1 Sandi Lam2 1Michael E. DeBakey Department of Surgery, Division of Plastic Surgery, 2Michael E. DeBakey Department of Surgery, Division of Neurosurgery, Baylor College of Medicine, Houston, TX,
Buchanan EP, Xue Y, Xue AS, Olshinka A, Lam S   +4 more
doaj  

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Identification of Novel Interacting Proteins of FUZ and GPR161

PROTEOMICS, EarlyView.
ABSTRACT Protein–protein interactions are central to the dynamic regulation of signaling pathways and provide critical insight into the cellular mechanisms underlying human disease. Our previous study demonstrated biochemical and genetic interactions between FUZ and GPR161 in sonic hedgehog signaling during spinal neural tube development. In this study,
Gabriella Salazar, Anna Battenhouse, Andrew J. Kim, Sung‐Eun Kim   +3 more
wiley   +1 more source