Results 131 to 140 of about 88,731 (270)
Central Nervous System Bleeding in Children With Haemophilia in Limited Resource
Haemophilia, EarlyView.ABSTRACT Introduction Central nervous system (CNS) bleeding in children with haemophilia is a life‐threatening complication that may cause severe neurological sequelae or death. In resource‐limited settings, where prophylaxis is not universally accessible, its patterns and outcomes may differ from those in high‐income countries.
Patcharee Komvilaisak +5 more
wiley +1 more source
Veterinary and Comparative Oncology, EarlyView.ABSTRACT Surgery is a common treatment for intracranial meningiomas in dogs, although the prognostic impact of the extent of resection (EOR) has not been systematically evaluated. This retrospective study identified prognostic factors associated with clinical outcomes in dogs that underwent surgery and early post‐operative magnetic resonance imaging ...
John H. Rossmeisl +6 more
wiley +1 more source
Reconstruction of an orbital fracture in a mare using a 3D‐printed patient‐specific implant
Veterinary Surgery, EarlyView.Abstract Objective To describe surgical repair of an orbital wall fracture communicating with the caudal maxillary sinus using a three dimensional (3D)‐printed, patient‐specific implant (PSI). Study design Case report. Animal A 25‐year‐old Haflinger mare (370 kg). Methods The mare presented with severe chemosis and emphysema of the left upper and lower
Jennifer Gernhardt +5 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Spinal cord injury (SCI) triggers immediate and widespread pathophysiological changes not only at the site of impact but also beyond it, including alterations in remote cortical regions. Here, we report early astrocytic changes in the cerebral cortex following SCI at birth, identified using two specific glial markers in an innovative in vitro ...
Luca Mio +4 more
wiley +1 more source
Mitochondrial control of ciliary gene expression and structure in striatal neurons
The Journal of Physiology, EarlyView.Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen +5 more
wiley +1 more source
Right medial temporal lobe mass in a 25‐year‐old male
Brain Pathology, EarlyView.
Jorge Samanamud +10 more
wiley +1 more source
Sound offset responses become highly informative in the auditory cortex
The Journal of Physiology, EarlyView.Abstract figure legend Using large datasets of neural responses to diverse sounds recorded across four stages of the mouse auditory system (depicted and colour‐coded on the left), offset responses occurring after the termination of each sound (time window indicated by the orange shaded area superimposed with activity traces) were characterized and it ...
Charly Lamothe +3 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A, schematic illustration of the ventral aspect of an ex vivo preparation of the entire CNS from a neonatal rat subjected to a calibrated thoracic impact. The trauma induced a large depolarising injury potential (DIP, black trace) recorded from the L5 ventral root (VRrL5), which was markedly reduced by transient receptor ...
Atiyeh Mohammadshirazi +5 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend In cortical layer (L)5 pyramidal neurons we found that mitochondria in the axon initial segment (AIS) are distributed non‐uniformly and display robust calcium (Ca2+) uptake during action potential (AP) firing. Because the AIS is the site for the initiation of APs, which are shaped by cytosolic Ca2+ levels, we hypothesized that ...
Koen Kole, Maarten H.P. Kole
wiley +1 more source