ABSTRACT ALK‐negative anaplastic large cell lymphoma (ALCL) is a rare primary central nervous system lymphoma (PCNSL). Although DUSP22 rearrangement is considered favorable in systemic ALK‐negative ALCL, survival remains poor in PCNSL. We report a case of PCNSL ALK‐negative ALCL with DUSP22‐IRF4 rearrangement and an unusual gain of the ALK gene (2p23),
Sindu Iska +5 more
wiley +1 more source
Development and validation of three risk prediction models for clinical deterioration of patients after craniotomy: a retrospective cohort study in China. [PDF]
Xu L +5 more
europepmc +1 more source
Abstract Background In skull‐base proton therapy (PT), severe toxicity outcomes such as temporal lobe necrosis (TLN) may be associated with inadequate management of the actual radiobiological effectiveness (RBE) of proton beams. Combining dose‐averaged linear energy transfer (LETd) and dose may be crucial in treatment plan optimization and evaluation ...
Giulia Fontana +9 more
wiley +1 more source
Neuropathic Cranial Pain Phenotypes After Craniotomy: A Large, Single-Center Retrospective Cohort Study. [PDF]
Shemesh SZ +7 more
europepmc +1 more source
ABSTRACT Background Postoperative complications substantially increase morbidity, mortality and healthcare costs. Understanding prognostic factors is essential for risk stratification, targeted prevention strategies, and development of prediction models.
Anders Peder Højer Karlsen +15 more
wiley +1 more source
Minimally-invasive resection of deep-seated subcortical and intraventricular lesions using an integrated camera-port system: A retrospective case series. [PDF]
Briggs RG +9 more
europepmc +1 more source
Metachronous Pineal Germinoma 11 Years After Total Resection of a Mature Teratoma
ABSTRACT Central nervous system germ cell tumors are uncommon and include germinomas, teratomas, and other nongerminomatous germ cell tumors. Mature teratomas are usually cured by complete resection, but rare patients later develop a histologically distinct malignant germ cell tumor.
Shunsuke Koga +7 more
wiley +1 more source
The role of bone flap explantation in the recurrence of surgical site infection after elective craniotomy: A multicenter propensity-matched cohort study. [PDF]
Lucia K +8 more
europepmc +1 more source
Protein kinase Cδ and pharmacomechanical coupling: Re‐envisioning cerebral vascular control
Abstract figure legend Top, G‐protein coupled receptors trigger electromechanical and pharmacomechanical coupling, the latter via signal transduction pathways that inhibit myosin light chain phosphatase. Middle, the relative contribution of electromechanical and pharmacomechanical coupling varies with the concentration and the vessel area to which ...
Nadia Haghbin +10 more
wiley +1 more source

