Results 101 to 110 of about 123,112 (334)

Postoperative Nausea and Vomiting After Craniotomy: An Evidence-based Review of General Considerations, Risk Factors, and Management

open access: yesJournal of Neurosurgical Anesthesiology, 2019
One of the most common and distressing symptoms after craniotomy is postoperative nausea and vomiting (PONV). PONV could generate delayed postanesthesia care and hospitalization discharge, lower patient satisfaction, and an increase in overall ...
Alberto A. Uribe   +6 more
semanticscholar   +1 more source

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo   +9 more
wiley   +1 more source

TULP4, a novel E3 ligase gene, participates in neuronal migration as a candidate in schizophrenia

open access: yesCNS Neuroscience &Therapeutics, EarlyView., 2023
Mutations identified from four SCZ pedigrees resulted in decreased TULP4 expression. Tulp4 knockdown caused delayed neuron migration in embryonic mice, and impaired cognition and prepulse inhibition in adult mice. These phenotypes may be related to TULP4 through its involvement in the formation of a novel E3 ubiquitin ligases.
Yan Bi   +19 more
wiley   +1 more source

Characteristics of temporal fluctuations in the hyperpolarized state of the cortical slow oscillation [PDF]

open access: yes, 2008
We present evidence for the hypothesis that transitions between the low- and high-firing states of the cortical slow oscillation correspond to neuronal phase transitions. By analyzing intracellular recordings of the membrane potential during the cortical
Barry, Melissa   +4 more
core   +2 more sources

Fabrication of High‐Density Multimodal Neural Probes Based on Heterogeneously Integrated CMOS

open access: yesAdvanced Science, EarlyView.
A chiplet‐based methodology democratizes active neural probe development on standard bulk CMOS services. This yields the first probe combining high‐density electrophysiology (416 electrodes) with calcium imaging (832 photodiodes) and complete on‐chip signal processing across 13 shanks.
Ju Hee Mun   +10 more
wiley   +1 more source

Reduced risk of venous thromboembolism with the use of intermittent pneumatic compression after craniotomy: a randomized controlled prospective study.

open access: yesJournal of Neurosurgery, 2019
OBJECTIVEThe term "venous thromboembolism" (VTE) subsumes deep venous thrombosis (DVT) and pulmonary embolism. The incidence of DVT after craniotomy was reported to be as high as 50%.
J. Prell   +6 more
semanticscholar   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

open access: yesAdvanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann   +11 more
wiley   +1 more source

Intravenous acetaminophen for postoperative supratentorial craniotomy pain: a prospective, randomized, double-blinded, placebo-controlled trial.

open access: yesJournal of Neurosurgery, 2019
In BriefThe authors designed a randomized, double-blinded, placebo-controlled trial to evaluate intravenous acetaminophen as a scheduled adjunct with our standardized craniotomy pain control regimen.
Walavan Sivakumar   +9 more
semanticscholar   +1 more source

Multi‐Functional Adaptive Interfaces for Next‐Generation Wearable and Implantable Bioelectronics

open access: yesAdvanced Science, EarlyView.
Adaptive Biointerfaces: A comprehensive overview of next‐generation bioelectronics is presented, highlighting mechano‐adaptive and biophysiologically adaptive interfaces that enable stable, long‐term integration with living tissues. As illustrated in the image, adaptive interface strategies, including mechano‐adaptivity (e.g., injectability, shape ...
Jinhong Park   +7 more
wiley   +1 more source

Evaluation of risk factors for postoperative neurologic intensive care admission after brain tumor craniotomy: A single-center longitudinal study

open access: yesJournal of Anaesthesiology Clinical Pharmacology
Background and Aims: Perioperative variable parameters can be significant risk factors for postoperative intensive care unit (ICU) admission after elective craniotomy for intracranial neoplasm, as assessed by various scoring systems such as Cranio Score.
Konish Biswas   +3 more
doaj   +1 more source

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