Results 91 to 100 of about 59,898 (219)

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade   +7 more
wiley   +1 more source

Evaluation of effects of intravenous infusion of dexmedetomidine or lignocaine on stress response and postoperative pain in patients undergoing craniotomy for intracranial tumors: A randomized controlled exploratory study

open access: yesSaudi Journal of Anaesthesia
Background: Goals of anesthesia in neurosurgery include stable cerebral hemodynamics and provide relaxed brain to surgeon. Dexmedetomidine and lignocaine as an adjuvant can fulfill these criteria but literature comparing the two are sparse.
Shivam Shekhar   +3 more
doaj   +1 more source

Framework for headache management in pediatric patients with stroke and cerebrovascular lesions: A narrative review

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To present a practical, evidence‐based framework for the management of headache disorders in pediatric patients with prior stroke or underlying cerebral vascular lesions, with particular attention to safety and efficacy of pharmacologic and non‐pharmacologic therapies.
Allison C. Hyland   +7 more
wiley   +1 more source

Optimal Healthcare Contracts: Theory and Empirical Evidence

open access: yesJournal of Economics &Management Strategy, EarlyView.
ABSTRACT In this paper, we investigate the contracts offered by a large healthcare purchaser to health service providers. Contracts are based on the DRG principle that all hospitalizations in a diagnosis group are reimbursed at the same rate. This principle is relaxed in practice, as in several cases, the amount reimbursed within each DRG exhibits ...
Paolo Berta   +2 more
wiley   +1 more source

Human dissection and comparative anatomy: Archaeological evidence for nineteenth‐century anatomical practice at University College London

open access: yesJournal of Anatomy, EarlyView.
Excavation at University College London revealed more than 8700 human skeletal fragments representing at least 38 individuals, alongside over 800 animal remains. Features consistent with dissection, specimen preparation and curation provide evidence for the use of human and animal material in nineteenth‐century anatomical education, offering rare ...
Wendy Birch, Tania Kausmally
wiley   +1 more source

An exploratory evaluation of the frequency of perioperative changes in electrolyte, acid–base, creatinine, glucose, and lactate variables in dogs and cats undergoing cranial surgery for tumor resection

open access: yesVeterinary Surgery, EarlyView.
Abstract Objective To explore the frequency and severity of abnormalities in perioperative point‐of‐care bloodwork in dogs and cats undergoing cranial surgery for tumor resection with particular emphasis on dyskalemia development. Study design Retrospective observational study. Animals A total of 61 dogs and 14 cats undergoing cranial surgery for tumor
Zoe E. Weiss   +4 more
wiley   +1 more source

Comparison treatments for basal ganglia hemorrhage: minimally invasive puncture and drainage versus craniotomy versus conservative treatment

open access: yesJournal of Comparative Effectiveness Research
Aim: The optimal management strategies for spontaneous intracerebral hemorrhage in the basal ganglia region are still controversial. The purpose of the present study is to evaluate the clinical benefits of craniotomy,minimally invasive puncture and ...
Tao Tang   +5 more
doaj   +1 more source

Anesthesia for Craniotomy [PDF]

open access: yesASA Refresher Courses in Anesthesiology, 2002
openaire   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen   +5 more
wiley   +1 more source

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