Results 11 to 20 of about 305,765 (260)

Analysis of Potential Co-Benefits for Bicyclist Crash Imminent Braking Systems [PDF]

, 2017
In the US, the number of traffic fatalities has had a long term downward trend as a result of advances in the crash worthiness of vehicles. However, these improvements in crash worthiness do little to protect other vulnerable road users such as ...
Chen, Yaobin, Chien, Stanley, Good, David H., Krutilla, Kerry, Li, Lingxi   +4 more
core   +1 more source

New Multiphase CP and DP 1000 MPa strength level grades for improved performance after hot forming [PDF]

, 2019
Pure martensitic steels have after hot forming limited performance in terms of rest ductility which limits the application in crash relevant parts. New steel grades were designed in the EU project HOTFORM including the corresponding process routes. These
Aranguren, Iñigo, Arribas, Maribel, Caro, Daniele De, Lahaije, C T W, Pérez, Iñaki, Rana, R, Sunderkoetter, C   +6 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

A new test procedure to validate tensile dynamic mechanical properties of sheet metals and alloys in automotive crash applications [PDF]

, 2008
A thin walled open channel beam subjected to a 3-point bend and constant velocity boundary condition is investigated to establish its potential to validate material performance for automotive crash applications.
Buckley, M.A., Schley, C.A., Wood, Paul
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Non-Parametric Analyses of Log-Periodic Precursors to Financial Crashes

, 2002
We apply two non-parametric methods to test further the hypothesis that log-periodicity characterizes the detrended price trajectory of large financial indices prior to financial crashes or strong corrections.
DIDIER SORNETTE, Erzan A., Johansen A., Johansen A., Johansen A., Johansen A., Johansen A., Press W., Sornette D., WEI-XING ZHOU   +9 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

NASA/FAA general aviation crash dynamics program [PDF]

, 1981
The program involves controlled full scale crash testing, nonlinear structural analyses to predict large deflection elastoplastic response, and load attenuating concepts for use in improved seat and subfloor structure.
Carden, H. D., Hayduk, R. J., Thomson, R. G.   +2 more
core   +1 more source