Results 41 to 50 of about 6,687,153 (243)
The “DLR Crash Report”: Towards a Standard Crash-Testing Protocol for Robot Safety - Part I: Results [PDF]
, 2009 After analyzing fundamental impact characteristics of robot-human collisions in our previous work, the intention in the present paper is to augment existing knowledge in this field, verify previously given statements with standardized equipment of the ...
Hirzinger, Gerd +4 more
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, 2021 This is a sample submission generated by Vireo to test the repository deposit features.Test ...
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Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
The executive pay gap and stock price crash risk: Promotion or suppression?
Frontiers in Psychology, 2023 BackgroundIn recent years, cases of stock price crash have continued to emerge. However, yet little research to date has investigated the compensation incentives of top management team (TMT) affect the risk of stock price crash.
Qi Liu, Zicheng Pan
doaj +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Advanced Manufacturing: Polymer & Composites Science, 2020 Carbon fiber reinforced polymer composites (CFRPC) are one of the promising lightweight materials in car production and show excellent energy absorption potential.
Florian Mischo +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Testing sensitivity of BILAN and GR2M models to climate conditions in the Gambia River Basin
Journal of Hydrology and HydromechanicsThis study investigates the performance of two lumped hydrological models, BILAN and GR2M, in simulating runoff across six catchments in the Gambia River Basin (Senegal) over a 30-year period employing a 7-year sliding window under different climatic ...
Ba Doudou +3 more
doaj +1 more source