Results 31 to 40 of about 6,687,153 (243)
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core +5 more sources
Near Side Crash Neck Injury, Crash Test and Accident data comparison
International Journal of Automotive EngineeringNear side crashes make up high mortality and serious injury rates. Side airbags protect vehicle occupants in near side crashes. In previous reports, the author analyzed the effect of side airbags and found that the effect of the torso protection side air
Kazuo Higuchi
doaj +1 more source
Dynamic tests of the culvert face within crashtests
Acta Polytechnica CTU Proceedings, 2022 Severity of a vehicle impact into solid obstacles alongside the road can be annually illustrated through accident statistics. One example of such solid obstacles is drainage ditch culvert faces.
Luboš Nouzovský +3 more
doaj +1 more source
Experimental Investigation of Unidirectional Glass-Fiber-Reinforced Plastics under High Strain Rates
Applied Mechanics, 2023 When a vehicle leaves the road, crash barriers stop it and prevent significant damage to the vehicle, its environment, and the occupants. Typically, such protection systems are made of simple steel, but fiber-reinforced composites can efficiently absorb ...
Sören Bieler +3 more
doaj +1 more source
Applied Sciences, 2022 This research assessed a mechanical coupling for the ISOFIX Child Restraint System using the Finite Element Method (FEM) in a critical condition (simultaneous frontal and lateral collision).
Iván Lenín Cruz-Jaramillo +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Simplified modeling of a wooden vehicle restraint system to reduce computation time
Mechanics & IndustryVehicle restraint systems (VRS) are components installed on roadsides or freeways to ensure the safety of road users. The validation of a VRS is conditioned by crash tests in accordance with standards EN 1317-1 and EN 1317-2.
Nyobe Charly Julien +3 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source