Results 131 to 140 of about 943,536 (329)

Neuroanatomical characterization of the Nmu-Cre knock-in mice reveals an interconnected network of unique neuropeptidergic cells [PDF]

, 2023
Mireia Medrano, Wissal Allaoui, Mathias Van Bulck, Sofie Thys, Leila Makrini-Maleville, Eve Seuntjens, Winnok H. De Vos, Emmanuel Valjent, Balázs Gaszner, Ann Van Eeckhaut, Ilse Smolders, Dimitri De Bundel   +11 more
openalex   +1 more source

Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang, Yuan Fang, Lingli Jin, Dongyang Liu, Yicheng Liu, Ruijia Zheng, Liyun Yong, Xin Wu, Longliang Qiao, Meiyan Wang, Fengfeng Cai   +10 more
wiley   +1 more source

The IRG mouse: A two‐color fluorescent reporter for assessing Cre‐mediated recombination and imaging complex cellular relationships in situ [PDF]

, 2008
Rita De Gasperi, Anne B. Rocher, Miguel A. Gama Sosa, Susan L. Wearne, Gissel M. Perez, Victor L. Friedrich, Patrick R. Hof, Gregory A. Elder   +7 more
openalex   +1 more source

Use of creative tools, technologies, processes and practices in the sectors of Art, Media, and Architecture: State-of the-Art and desired future scenarios [PDF]

, 2015
The aim of the paper is to analyse and present the preliminary findings of the EU FP7 funded CRe-AM project for the Art, Media, and Architecture sectors. This project bridges communities of technology providers and innovators with the creative industries,
Abbasi, M, Matich, M, Payne, A, Smith, C, Stergioulas, LK, Vassilopoulou, P   +5 more
core  

Fibroblast Activation Protein Promotes Thoracic Aortic Dissection via PLAUR/ITGB1‐Mediated Pro‐inflammatory Macrophage Polarization

Advanced Science, EarlyView.
This study reveals that FAP promotes thoracic aortic dissection (TAD) through a nonenzymatic mechanism involving fibroblast‐macrophage crosstalk via the FAP/PLAUR/ITGB1/FAK axis. Targeting this pathway might offer a promising therapeutic strategy for TAD.
Hongqiao Zhu, Jianlie Wu, Ziyi Xu, Yifei Pei, Zaiping Jing, Jian Zhou, Rui Feng, Junjun Liu   +7 more
wiley   +1 more source

Climate Change and Economic Sustainability: Empirical Evidence on the Dynamics of Adjusted Net Savings in Benin's Regions

Climate Resilience and Sustainability
The economic sustainability of territories is a key issue in ensuring the well‐being of future generations. In accordance with the neoclassical theoretical approach, this article analyzes the dynamics of adjusted net savings (ANSs) in Benin's regions in ...
Christian Duhamel Logozo, Vihoutou Médjikouê Marthe Kougblenou Menou   +1 more
doaj   +1 more source

Capturing reaction paths and intermediates in Cre- loxP recombination using single-molecule fluorescence [PDF]

, 2012
Justin N. M. Pinkney, Paweł Zawadzki, Jarosław Mazuryk, Lidia K. Arciszewska, David J. Sherratt, Achillefs N. Kapanidis   +5 more
openalex   +1 more source

A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages [PDF]

, 2023
Simone Brioschi, Julia A. Belk, Vincent Peng, Martina Molgora, Patrick Fernandes Rodrigues, Khai M. Nguyen, Shoutang Wang, Siling Du, Wei-Le Wang, Gary E. Grajales‐Reyes, Jennifer M. Ponce, Carla M. Yuede, Qingyun Li, John Baer, David G. DeNardo, Susan Gilfillan, Marina Cella, Ansuman T. Satpathy, Marco Colonna   +18 more
openalex   +1 more source

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

Advanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang, Gaoge Sun, Xiangzheng Liu, Shuai Zuo, Pengyuan Wang, Boxiao Zhan, Zhi John Lu, Hang Yin, Ying Zhang   +8 more
wiley   +1 more source

Trehalose Activates CRE-Dependent Transcriptional Signaling in HT22 Mouse Hippocampal Neuronal Cells: A Central Role for PKA Without cAMP Elevation [PDF]

, 2018
Erik Maronde
openalex   +1 more source